miRBase entry: mmu-mir-99a

Stem-loop mmu-mir-99a


Accession
MI0000146
Symbol
MGI: Mir99a
Description
Mus musculus mmu-mir-99a precursor miRNA
Gene family
MIPF0000033; mir-10

Literature search
66 open access papers mention mmu-mir-99a
(778 sentences)

Sequence

414559 reads, 1842 reads per million, 107 experiments
cauaAACCCGUAGAUCCGAUCUUGUGgugaaguggaccgcgCAAGCUCGUUUCUAUGGGUCUgug
((((.(((((((((..(((.((((((((.......)))..))))).)))..))))))))).))))

Structure
    A         UC   U     --   ga 
caua ACCCGUAGA  CGA CUUGU  Ggu  a
|||| |||||||||  ||| |||||  |||  g
gugU UGGGUAUCU  GCU GAACg  cca  u
    C         UU   C     cg   gg 


Annotation confidence High
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Comments
The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [3]. The 5' end of the miRNA may be offset with respect to previous annotations.

Genome context
chr16: 77598936-77599000 [+]
Clustered miRNAs
1 other miRNA is < 10 kb from mmu-mir-99a
Name Accession Chromosome Start End Strand Confidence




Database links

Mature mmu-miR-99a-5p

Accession MIMAT0000131
Description Mus musculus mmu-miR-99a-5p mature miRNA
Sequence 5 - AACCCGUAGAUCCGAUCUUGUG - 26
Evidence experimental
cloned [1-3], Illumina [4-5]
Database links
Predicted targets

Mature mmu-miR-99a-3p

Accession MIMAT0016981
Description Mus musculus mmu-miR-99a-3p mature miRNA
Sequence 42 - CAAGCUCGUUUCUAUGGGUCU - 62
Evidence experimental
Illumina [5]
Database links
Predicted targets

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 12007417
    Identification of tissue-specific microRNAs from mouse
    "Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T"
    "Curr Biol (2002) 12:735-739

  3. PubMed ID: 16766679
    Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes
    "Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N, Imai H"
    "Genes Dev (2006) 20:1732-1743

  4. PubMed ID: 20215419
    MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
    "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
    "Mol Hum Reprod (2010) 16:463-471

  5. PubMed ID: 20413612
    Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
    "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
    "Genes Dev (2010) 24:992-1009