miRBase entry: dme-mir-4

Stem-loop dme-mir-4


Accession
MI0000122
Description
Drosophila melanogaster dme-mir-4 precursor miRNA
Gene family
MIPF0000305; mir-4

Literature search
6 open access papers mention dme-mir-4
(21 sentences)

Sequence

27504 reads, 4306 reads per million, 42 experiments
uugcaauuaguuuCUUUGGUCGUCCAGCCUUAGGUGAuuuuuccggucAUAAAGCUAGACAACCAUUGAaguucguugugg
..(((((.((((((..((((.(((.(((.((..((((((.....)))))).))))).))).))))..)))))).)))))..

Structure
uu     u      UU    C   C   C  AG      u 
  gcaau aguuuC  UGGU GUC AGC UU  GUGAuu u
  ||||| ||||||  |||| ||| ||| ||  |||||| u
  uguug uugaAG  ACCA CAG UCG AA  UAcugg c
gg     c      UU    A   A   -  -A      c 


Annotation confidence High
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Genome context
chr2R: 19661289-19661369 [-]
Clustered miRNAs
7 other miRNAs are < 10 kb from dme-mir-4
Name Accession Chromosome Start End Strand Confidence




Database links

Mature dme-miR-4-3p

Accession MIMAT0000109
Description Drosophila melanogaster dme-miR-4-3p mature miRNA
Sequence 49 - AUAAAGCUAGACAACCAUUGA - 69
Evidence experimental
cloned [1,3], Northern [1-3], 454 [4-5], Illumina [5]
Database links
Predicted targets

Mature dme-miR-4-5p

Accession MIMAT0020785
Description Drosophila melanogaster dme-miR-4-5p mature miRNA
Sequence 14 - CUUUGGUCGUCCAGCCUUAGGUGA - 37
Evidence not_experimental
Database links

References

  1. PubMed ID: 11679670
    Identification of novel genes coding for small expressed RNAs
    "Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T"
    "Science (2001) 294:853-858

  2. PubMed ID: 12812784
    Temporal regulation of microRNA expression in Drosophila melanogaster mediated by hormonal signals and broad-Complex gene activity
    "Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V"
    "Dev Biol (2003) 259:9-18

  3. PubMed ID: 12919683
    The small RNA profile during Drosophila melanogaster development
    "Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B, Gaasterland T, Meyer J, Tuschl T"
    "Dev Cell (2003) 5:337-350

  4. PubMed ID: 17989254
    Evolution, biogenesis, expression, and target predictions of a substantially expanded set of Drosophila microRNAs
    "Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC"
    "Genome Res (2007) 17:1850-1864

  5. PubMed ID: 17989255
    Systematic discovery and characterization of fly microRNAs using 12 Drosophila genomes
    "Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis M"
    "Genome Res (2007) 17:1865-1879