miRBase entry: dme-mir-1

Stem-loop dme-mir-1


Accession
MI0000116
Description
Drosophila melanogaster dme-mir-1 precursor miRNA
Gene family
MIPF0000038; mir-1

Literature search
46 open access papers mention dme-mir-1
(226 sentences)

Sequence

19806361 reads, 107366 reads per million, 49 experiments
uucagccuuugagaguuCCAUGCUUCCUUGCAUUCAAUAguuauauucaagcauaUGGAAUGUAAAGAAGUAUGGAGcgaaaucuggcgag
.((.(((.......((((((((((((.((((((((.((((((.......))).))).)))))))).)))))))))))).......))))).

Structure
u  a   uuugaga            C        A   -   au 
 uc gcc       guuCCAUGCUUC UUGCAUUC AUA guu  a
 || |||       |||||||||||| |||||||| ||| |||  u
 ag cgg       cGAGGUAUGAAG AAUGUAAG Uau cga  u
g  -   ucuaaag            A        G   a   ac 


Annotation confidence High
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Genome context
chr2L: 20487441-20487531 [+]

Database links

Mature dme-miR-1-3p

Accession MIMAT0000105
Description Drosophila melanogaster dme-miR-1-3p mature miRNA
Sequence 56 - UGGAAUGUAAAGAAGUAUGGAG - 77
Evidence experimental
cloned [1,3], Northern [1-2], 454 [4-5], Illumina [5]
Database links
Predicted targets

Mature dme-miR-1-5p

Accession MIMAT0020779
Description Drosophila melanogaster dme-miR-1-5p mature miRNA
Sequence 18 - CCAUGCUUCCUUGCAUUCAAUA - 39
Evidence not_experimental
Database links

References

  1. PubMed ID: 11679670
    Identification of novel genes coding for small expressed RNAs
    "Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T"
    "Science (2001) 294:853-858

  2. PubMed ID: 12812784
    Temporal regulation of microRNA expression in Drosophila melanogaster mediated by hormonal signals and broad-Complex gene activity
    "Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V"
    "Dev Biol (2003) 259:9-18

  3. PubMed ID: 12919683
    The small RNA profile during Drosophila melanogaster development
    "Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B, Gaasterland T, Meyer J, Tuschl T"
    "Dev Cell (2003) 5:337-350

  4. PubMed ID: 17989254
    Evolution, biogenesis, expression, and target predictions of a substantially expanded set of Drosophila microRNAs
    "Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC"
    "Genome Res (2007) 17:1850-1864

  5. PubMed ID: 17989255
    Systematic discovery and characterization of fly microRNAs using 12 Drosophila genomes
    "Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis M"
    "Genome Res (2007) 17:1865-1879