Mature hsa-miR-181c-5p
| Accession | MIMAT0000258 |
| Description | hsa-miR-181c-5p mature miRNA |
| Hairpins | |
| Sequence | AACAUUCAACCUGUCGGUGAGU |
| Evidence |
experimental
cloned [2] |
| Database links |
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| Predicted targets |
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QuickGo Function
QuickGO is a fast web-based browser of the Gene Ontology and Gene Ontology annotation data.
| Qualifier | GO term | Evidence | Reference | Annotation Extension |
|---|---|---|---|---|
| acts_upstream_of | GO:0032700 negative regulation of interleukin-17 production |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:25962782 | occurs_in CL:2000001 |
| acts_upstream_of | GO:0032703 negative regulation of interleukin-2 production |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:21112091 | occurs_in CL:0000084 |
| acts_upstream_of | GO:0032716 negative regulation of interleukin-7 production |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:25962782 | occurs_in CL:2000001 |
| acts_upstream_of | GO:0046007 negative regulation of activated T cell proliferation |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:21112091 | |
| acts_upstream_of | GO:0050868 negative regulation of T cell activation |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:21112091 | |
| acts_upstream_of | GO:1901646 negative regulation of synoviocyte proliferation |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:28379604 | |
| enables | GO:0003727 single-stranded RNA binding |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:28379604 | |
| enables | GO:1903231 mRNA base-pairing translational repressor activity |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:21112091 | has_input UniProtKB:P60568 |
| enables | GO:1903231 mRNA base-pairing translational repressor activity |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:25535255 | has_input UniProtKB:P01375 |
| enables | GO:1903231 mRNA base-pairing translational repressor activity |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:25962782 | occurs_in CL:2000001 |
| enables | GO:1903231 mRNA base-pairing translational repressor activity |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:28379604 | has_input UniProtKB:P10451 |
| enables | GO:1903231 mRNA base-pairing translational repressor activity |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:31172560 | has_input UniProtKB:P01583 |
| involved_in | GO:0001774 microglial cell activation |
ECO:0000250 sequence similarity evidence used in manual assertion |
PMID:GO_REF:0000024 | |
| involved_in | GO:0031047 regulatory ncRNA-mediated gene silencing |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:28379604 | |
| involved_in | GO:0032690 negative regulation of interleukin-1 alpha production |
ECO:0000250 sequence similarity evidence used in manual assertion |
PMID:31172560 | |
| involved_in | GO:0032716 negative regulation of interleukin-7 production |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:25962782 | |
| involved_in | GO:0035195 miRNA-mediated post-transcriptional gene silencing |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:25962782 | has_input UniProtKB:P13232 |
| involved_in | GO:0035195 miRNA-mediated post-transcriptional gene silencing |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:28379604 | has_input UniProtKB:P10451 |
| involved_in | GO:0035195 miRNA-mediated post-transcriptional gene silencing |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:31172560 | has_input UniProtKB:P01583 |
| involved_in | GO:0035278 miRNA-mediated gene silencing by inhibition of translation |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:21112091 | has_input UniProtKB:P60568 |
| involved_in | GO:0035279 miRNA-mediated gene silencing by mRNA destabilization |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:25535255 | has_input UniProtKB:P01375 |
| involved_in | GO:0043524 negative regulation of neuron apoptotic process |
ECO:0000250 sequence similarity evidence used in manual assertion |
PMID:GO_REF:0000024 | |
| involved_in | GO:0050728 negative regulation of inflammatory response |
ECO:0000250 sequence similarity evidence used in manual assertion |
PMID:GO_REF:0000024 | |
| involved_in | GO:0050728 negative regulation of inflammatory response |
ECO:0000315 mutant phenotype evidence used in manual assertion |
PMID:28379604 | |
| involved_in | GO:0061889 negative regulation of astrocyte activation |
ECO:0000250 sequence similarity evidence used in manual assertion |
PMID:GO_REF:0000024 |
StarBase
MicroRNA-mRNA interaction maps from Argonaute CLIP-Seq and Degradome-Seq data.
| Target Gene ID | Target Gene Name | Number of supporting experiments | Number of target-predicting programs | Maximum number of target sites | Chromosome | Target-predicting region start | Target-predicting region end | Strand |
|---|
miR2Disease
A manually curated database, aimed at providing a comprehensive resource of miRNA deregulation in various human diseases.
Click here for more information and to obtain references for the studies.
| Disease | Differential expression | Experiment | Year | Study |
|---|
