miRBase entry: hsa-miR-18a-5p

Mature hsa-miR-18a-5p

Accession MIMAT0000072
Description hsa-miR-18a-5p mature miRNA
Hairpins
Sequence UAAGGUGCAUCUAGUGCAGAUAG
Evidence experimental
cloned [1,3-6], Northern [1]
Database links
Predicted targets


QuickGo Function

QuickGO is a fast web-based browser of the Gene Ontology and Gene Ontology annotation data.

Qualifier GO term Evidence Reference Annotation Extension
enables GO:1903231
mRNA base-pairing translational repressor activity
ECO:0000314
direct assay evidence used in manual assertion
PMID:20940405 has_input
UniProtKB:Q13485
enables GO:1903231
mRNA base-pairing translational repressor activity
ECO:0000314
direct assay evidence used in manual assertion
PMID:21067317 has_input
UniProtKB:Q8NFP9
enables GO:1903231
mRNA base-pairing translational repressor activity
ECO:0000314
direct assay evidence used in manual assertion
PMID:21145484 has_input
UniProtKB:Q13485
enables GO:1903231
mRNA base-pairing translational repressor activity
ECO:0000314
direct assay evidence used in manual assertion
PMID:21145484 has_input
UniProtKB:Q15796
enables GO:1903231
mRNA base-pairing translational repressor activity
ECO:0000314
direct assay evidence used in manual assertion
PMID:24169826 has_input
UniProtKB:P31994
enables GO:1903231
mRNA base-pairing translational repressor activity
ECO:0000314
direct assay evidence used in manual assertion
PMID:28131417 has_input
UniProtKB:P37173
enables GO:1903231
mRNA base-pairing translational repressor activity
ECO:0000314
direct assay evidence used in manual assertion
PMID:29988076 has_input
UniProtKB:P36956
involved_in GO:0010719
negative regulation of epithelial to mesenchymal transition
ECO:0000315
mutant phenotype evidence used in manual assertion
PMID:28131417 occurs_in
CL:1000491
involved_in GO:0030512
negative regulation of transforming growth factor beta receptor signaling pathway
ECO:0000314
direct assay evidence used in manual assertion
PMID:21145484
involved_in GO:0030512
negative regulation of transforming growth factor beta receptor signaling pathway
ECO:0000315
mutant phenotype evidence used in manual assertion
PMID:28131417 has_input
UniProtKB:P37173
involved_in GO:0035195
miRNA-mediated post-transcriptional gene silencing
ECO:0000314
direct assay evidence used in manual assertion
PMID:20940405 has_input
UniProtKB:Q13485
involved_in GO:0035195
miRNA-mediated post-transcriptional gene silencing
ECO:0000314
direct assay evidence used in manual assertion
PMID:21067317 has_input
UniProtKB:Q8NFP9
involved_in GO:0035195
miRNA-mediated post-transcriptional gene silencing
ECO:0000314
direct assay evidence used in manual assertion
PMID:21145484 has_input
UniProtKB:Q13485
involved_in GO:0035195
miRNA-mediated post-transcriptional gene silencing
ECO:0000314
direct assay evidence used in manual assertion
PMID:21145484 has_input
UniProtKB:Q15796
involved_in GO:0035195
miRNA-mediated post-transcriptional gene silencing
ECO:0000314
direct assay evidence used in manual assertion
PMID:24169826 has_input
UniProtKB:P31994
involved_in GO:0035279
miRNA-mediated gene silencing by mRNA destabilization
ECO:0000314
direct assay evidence used in manual assertion
PMID:28131417 has_input
UniProtKB:P37173
involved_in GO:0035279
miRNA-mediated gene silencing by mRNA destabilization
ECO:0000314
direct assay evidence used in manual assertion
PMID:29988076 has_input
UniProtKB:P36956
involved_in GO:0050861
positive regulation of B cell receptor signaling pathway
ECO:0000314
direct assay evidence used in manual assertion
PMID:24169826
involved_in GO:1901202
negative regulation of extracellular matrix assembly
ECO:0000315
mutant phenotype evidence used in manual assertion
PMID:28131417
involved_in GO:1903671
negative regulation of sprouting angiogenesis
ECO:0000314
direct assay evidence used in manual assertion
PMID:20299512
involved_in GO:1903845
negative regulation of cellular response to transforming growth factor beta stimulus
ECO:0000315
mutant phenotype evidence used in manual assertion
PMID:28131417 has_input
UniProtKB:P01137
involved_in GO:1905932
positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching
ECO:0000250
sequence similarity evidence used in manual assertion
PMID:GO_REF:0000024 occurs_in
CL:0000359
located_in GO:0005615
extracellular space
ECO:0007005
high throughput direct assay evidence used in manual assertion
PMID:18766170 part_of
UBERON:0001969
located_in GO:0005615
extracellular space
ECO:0007005
high throughput direct assay evidence used in manual assertion
PMID:26646931 part_of
UBERON:0001969
located_in GO:0048471
perinuclear region of cytoplasm
ECO:0000250
sequence similarity evidence used in manual assertion
PMID:GO_REF:0000024 part_of
CL:0000746

StarBase

MicroRNA-mRNA interaction maps from Argonaute CLIP-Seq and Degradome-Seq data.

Target Gene ID Target Gene Name Number of supporting experiments Number of target-predicting programs Maximum number of target sites Chromosome Target-predicting region start Target-predicting region end Strand

miR2Disease

A manually curated database, aimed at providing a comprehensive resource of miRNA deregulation in various human diseases.

Click here for more information and to obtain references for the studies.

Disease Differential expression Experiment Year Study