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6 publications mentioning hsa-mir-1273h

Open access articles that are associated with the species Homo sapiens and mention the gene name mir-1273h. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

[+] score: 46
Other miRNAs from this paper: hsa-mir-1273c
We found that miR-1273h-3p has 38 target genes. [score:3]
Arrangement of the miR-1273 Family's Binding Sites in the mRNA of Target Genes. [score:3]
This analysis of the localization of paired miR-1273 binding sites in the mRNA of target genes leads to the conclusion that they evolved from a common ancestor. [score:3]
The adaptation of miRNA binding sites to each member of the miR-1273 family or to their combinations could also be due to the evolution of target gene mRNA and their varying functions. [score:3]
Such compactness in the binding site location of the miR-1273 family could be a result of embedding one general nucleotide sequence into the target genes. [score:3]
We found that miR-1273h-5p has 127 binding sites on 126 target gene mRNAs. [score:3]
The mRNA of these target genes have only one miR-1273h-3p binding site. [score:3]
Some members of the miR-1273 family have a greater number of target genes than others. [score:3]
The distances described above between the pair binding sites of the miR-1273 family are nearly always matched in the target gene mRNA. [score:3]
The complementary nucleotide sequence to pre-miR-1273h includes binding sites for the miR-1273 family, and it is the most probable precursor for these segments (Figure 12). [score:1]
With a length of 21 nt, miR-1273h-5p is coded in the intergenic sequence of chromosome 16. [score:1]
Members of the miR-1273 family have different origins, lengths, quantities, and properties of the miRNA binding sites, among other features. [score:1]
Both miR-1273g-3p and miR-1273c have two overlapped nucleotides and pair binding sites, whose schemes are shown in Figure 8. The nucleotide sequences of miR-1273g-3p and miR-1273h have 16 overlapped nucleotides (Figure 12) that correspond to overlapping of their binding sites, shown in Figure 11. [score:1]
The segments of the 5′UTR in the CNGA1 and NFYC genes that contain the miR-1273g-3p and miR-1273h-5p binding sites are shown in Figure 11. [score:1]
The nucleotides of the miR-1273g-3p and miR-1273h-5p binding sites code polypeptides of different ORFs. [score:1]
This study revealed that several hundred mRNAs have homologous nucleotide sequences containing binding sites for members of the miR-1273 family. [score:1]
The distance between the miR-1273g-3p and miR-1273h-5p binding sites located in the CDSs of four genes is 12 nucleotides. [score:1]
With a length of 21 nt, miR-1273h-3p is coded in the intergenic nucleotide sequence of chromosome 16. [score:1]
A feature of the miR-1273 family that this study discovered is the presence of pair binding sites in mRNA segments of 100 nucleotides. [score:1]
The nucleotide sequences of the 3′UTRs indicate that paired miR-1273g-3p and miR-1273h-5p binding sites are located similarly to those in 5′UTRs and CDSs, with a separation distance of 12 nucleotides (Figure 11). [score:1]
The distances between miR-1273g-3p and miR-1273h-5p (Figure 12) and between their pair binding sites (Figure 11) are each 13 nucleotides. [score:1]
Features of the miR-1273 Family. [score:1]
The distance between the miR-1273g-3p and miR-1273h-5p binding sites is 12 nucleotides. [score:1]
No paired binding sites are found for miR-1273g-3p and miR-1273h-3p in any of the mRNA locations described above. [score:1]
Arrangement of the Binding Sites of the miR-1273 Family in mRNA. [score:1]
However, all of the pair binding sites of the miR-1273 family have deviations of one-two nucleotides between them. [score:1]
Specifically, we examined pairs composed of miR-1273g-3p with another member of the miR-1273 family. [score:1]
Highly conserved binding sites of miR-1273 family in a large number of genes testify about their emergence in the early stages in human evolution. [score:1]
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[+] score: 12
The down-regulated miRNAs miR-29b, miR-124, miR-6980, miR-1273h and miR-30c each are associated with at least 5 concordantly up-regulated target genes, with the only observed exceptions being the down-regulation of CCL2 and TNF. [score:12]
[1 to 20 of 1 sentences]
[+] score: 3
A total of twelve miRNAs were found to be commonly regulated over time in these three tissues; let-7d, let-7e, miR-1249, miR-1254, miR-1255, miR-1273, miR-1285, miR-1301, miR-1306, miR-548, and miR-8078. [score:2]
Binding sites of the miR-1273 family, miR-1285-3p and miR-5684 in human mRNAs. [score:1]
[1 to 20 of 2 sentences]
[+] score: 1
As demonstrated in Supplementary Table S1, five miRNAs belong to the hsa-miR-1273 family, which does not have well-documented anti-/pro-cancer properties, while among detected four members of the hsa-miR-30 family, hsa-miR-30c is reportedly involved promoting the invasiveness of metastatic breast cancer cells 11. [score:1]
[1 to 20 of 1 sentences]
[+] score: 1
01720Xhsa-miR-652-3p0.1640.00214Xhsa-miR-1273 g-3p0.3820.005491hsa-miR-21-5p0.1650.0005917hsa-miR-4668-5p0.3860.000139hsa-miR-142-5p0.1750.0005617hsa-miR-20b-3p0.3900.01073Xhsa-miR-36530.1780.0011722hsa-miR-148a-3p0.3910.000757hsa-miR-27b-3p0.1880.001339hsa-miR-483-3p0.3921.4E-0511hsa-miR-299-3p0.1910.0011214hsa-miR-44500.3930.000684hsa-miR-1260a0.1937.5E-0514hsa-miR-93-5p0.4000.007367hsa-miR-4445-5p0.2028.2E-053hsa-miR-56840.4050. [score:1]
[1 to 20 of 1 sentences]
[+] score: 1
The top ten miRNAs with the highest absolute loadings for the first principal component (PC1) were hsa-miR-30a-5p, hsa-miR-1273h-3p, hsa-miR-30a-3p, hsa-miR-30c-2–3p, hsa-miR-10b-5p, hsa-miR-199a-5p, hsa-miR-204-5p, hsa-miR-4433b-5p, hsa-miR-6852-5p and hsa-miR-126-3p. [score:1]
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