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2 publications mentioning hsa-mir-4685

Open access articles that are associated with the species Homo sapiens and mention the gene name mir-4685. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

[+] score: 16
We also included miR-4685-3p for comparison in further analyses, because miR-4685-3p potentially targeted MEK2, a downstream target of KRAS, based on an in silico prediction obtained with Target Scan 6.2 software [23] (Figure 1a). [score:7]
After screening for SRE/AP1 activity, we identified miR-4689 and miR-4685-3p as potent inhibitors in the RAF/MEK/ERK or MEKK/SEK/JNK pathway. [score:3]
Furthermore, miR-4689, but not miR-4685-3p, significantly inhibited cell proliferation in these cell lines (Figure 2b). [score:3]
It is of interest that miR-4689, but not miR-4685-3p, inhibited proliferation of mutant KRAS SW480 cells, and that only miR-4689 could correct altered RAF/MEK/ERK activity (Figure 2). [score:3]
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[+] score: 1
000631hsa-miR-296-5p2.710.0495120hsa-miR-4685-3p5.040.0009010hsa-miR-150-5p2.850.0092719hsa-miR-23c5.110.00081Xhsa-miR-45402.860.012809hsa-miR-5002-3p5.140.000353hsa-miR-42682.970.009692hsa-miR-56895.330.000546hsa-miR-12363.080.048776hsa-miR-9355.430.0018719hsa-miR-221-5p3.160.03132Xhsa-miR-374b-3p5.795.4E-05Xhsa-miR-36853.260.0035612hsa-miR-1255b-2-3p5.830.008231hsa-let-7d-3p3.350.021539hsa-miR-485-3p6.000. [score:1]
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