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6 publications mentioning hsa-mir-4485

Open access articles that are associated with the species Homo sapiens and mention the gene name mir-4485. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 24
Differentially expression type microRNA name Mean ratio Up-regulated hsa-miR-193b 2.1165 hsa-miR-34a 3.1282 hsa-miR-100 2.3189 hsa-miR-4485 2.6155 Down-regulated hsa-miR-3690 0.4276 hsa-miR-124 0.3538 hsa-miR-183 0.3946 hsa-miR-3935 0.3999 hsa-miR-451 0.4126 hsa-miR-4538 0.3603 hsa-miR-4701 0.4249 Figure 1 Hierarchical clustering analysis between 5 SALS patients and 5 healthy controls based on differentially expressed miRNAs. [score:11]
Differentially expression type microRNA name Mean ratio Up-regulated hsa-miR-193b 2.1165 hsa-miR-34a 3.1282 hsa-miR-100 2.3189 hsa-miR-4485 2.6155 Down-regulated hsa-miR-3690 0.4276 hsa-miR-124 0.3538 hsa-miR-183 0.3946 hsa-miR-3935 0.3999 hsa-miR-451 0.4126 hsa-miR-4538 0.3603 hsa-miR-4701 0.4249 Figure 1 Hierarchical clustering analysis between 5 SALS patients and 5 healthy controls based on differentially expressed miRNAs. [score:11]
Four miRNAs, including hsa-miR-34a, hsa-miR-100, hsa-miR-193b, hsa-miR-4485, with significantly higher expression levels were identified in the SALS group compared with those in the healthy control group (mean ratio = 2.11−3.12, p < 0.05, Table 2, Figure 1). [score:2]
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2
[+] score: 11
Other miRNAs from this paper: hsa-mir-1973
Moreover, they reported that hsa-miR-1973 and hsa-miR-4485 are upregulated in senescent endothelial cells and propose that these miRs are derived from the ASncmtRNA-2 stem by Dicer processing [50]. [score:4]
Transfection of hsa-miR-4485-3p results in downregulation of survivin and N-cadherin levels in MDA-MB-231 cells (Fitzpatrick and Briones, unpublished results). [score:4]
Indeed, we found that following ASK, MDA-MB-231 (human breast carcinoma) cells with ASO-1537S [6] for 24 h, hsa-miR-1973 and hsa-miR-4485 are overexpressed about 7-10 times compared to control cells (M. Briones and C. Fitzpatrick, unpublished results). [score:2]
Although murine homologues of hsa-miR-1973 and hsa-miR-4485 cannot be currently found in miR databases, the corresponding regions on the mASncmtRNAs display sequence identities of 100% to human for miR-1973, 93% for miR-4485-5p and 90% for miR-4485-3p, suggesting that these segments on the double-stranded region of the ASncmtRNAs could give rise to murine homologues of the corresponding miRs. [score:1]
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3
[+] score: 7
We found that IFN-γ and TNF-α resulted in up-regulation of miR-155–5p, miR-4485–3p, miR-218–5p, and miR-146a–5p and down-regulation of miR-582–5p, miR-582–3p, miR-93–5p, miR-217 and miR-125b–5p (supplemental Tables S1 and S2). [score:7]
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4
[+] score: 4
Nineteen of the downregulated miRNAs in chronic patients were found to be associated with carcinogenesis in various organs and tissues, such as miR-1207 [40], miR-3162-5p [41, 42], miR-3196 [43, 44], miR-371b-5p [45], miR-574-5p [46, 47], miR-1225-5p [48], miR-4485 [49], miR-572 [50], miR-4299 [51], miR-3679-5p [52], miR-3940-5p [53], miR-638 [54, 55], miR-1202 [56], miR-5787 [57], miR-1973 [58], miR-4532 [59], miR-1275 [60], miR-4728-5p [61], and miR-1915-3p [62]. [score:4]
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5
[+] score: 1
The analysis showed that only four miRNAs: hsa-miR-4461, hsa-miR-4463, hsa-miR-4484 and hsa-miR-4485 aligned to mitochondrial genome at positions (10690–10712), (13050–13068), (5749–5766) and (2562–2582) corresponding to ND4L, ND5, L-ORF and 16S rRNA genes respectively. [score:1]
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6
[+] score: 1
90 Down 3.84E-18 hsa-miR-4448 2.45 Up 1.66E-04 hsa-miR-1250 −5.71 Down 2.05E-169 hsa-miR-4426 2.23 Up 3.53E-05 hsa-miR-139-5p −5.46 Down 3.71E-25 hsa-miR-720 2.08 Up 1.21E-05 hsa-miR-335-5p −5.26 Down 2.00E-41 hsa-miR-4485 1.71 Up 6.14E-08 hsa-miR-362-3p −5.01 Down 3.36E-10 hsa-miR-877-5p 1.68 Up 1.92E-82 hsa-miR-1255a −4.92 Down 1.25E-62 hsa-miR-3679-5p 1.45 Up 5.53E-04 hsa-miR-3622a-5p −4.83 Down 4.30E-09 hsa-miR-21-3p 1.40 Up 7.87E-13 hsa-miR-1293 −4.67 Down 2.87E-08 hsa-miR-2116-3p −4.64 Down 3.67E-14 hsa-miR-365a-3p −4. [score:1]
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