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8 publications mentioning hsa-mir-4484

Open access articles that are associated with the species Homo sapiens and mention the gene name mir-4484. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 20
Among these: 3 miRNAs (i. e. miR-26a-5p, miR-143-3p, and miR-4454) were expressed in both RAA and LAA; 6 miRNAs (i. e. miR-30c-5p, miR-125b-5p, miR-133b, miR- 145-5p, miR-451a, and miR-4484) were expressed in only RAA; and 3 miRNAs (i. e. miR-1, miR-23b-3p, and miR-494) were expressed in only LAA. [score:7]
miR-4454 cannot be predicted using 5 target prediction databases, while, miR-4484 can be predicted using 2 target prediction databases. [score:5]
To determine the probable biological function of the AF -associated miRNAs, we predicted the putative targets and pathways of 10 validated miRNAs (i. e. miR-1, miR-23b-3p, miR-26a-5p, miR-30c-5p, miR-125b-5p, miR-133b, miR-143-3p, miR-145-5p, miR-4454, and miR-4484) using the miRFocus database. [score:3]
Most of these miRNAs were predicted by 5 target prediction databases except miR-4454 and miR-4484. [score:3]
To date, the miR-23, miR-125, miR-143, miR-145, miR-4454, and miR-4484 have not been described as participating in AF pathology. [score:1]
According to the qRT-PCR data, miR-26a-5p, miR-143-3p, miR-4454 were AF -associated miRNAs found in both RAA and LAA tissues, while miR-30c-5p, miR-125b-5p, miR-133b, miR-145-5p, miR-4484 were AF -associated miRNAs found in only RAA tissues and miR-1, miR-23b-3p were found only in LAA tissues (Figure  5). [score:1]
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2
[+] score: 7
Among the miRNAs, the function of fifteen downregulated miRNAs (miR-1587, miR-4505, miR-1915-3p, miR-4466, miR-3162-5p, miR-4484, miR-5001-5p, miR-3940-5p, miR-4687-3p, miR-6068, miR-548ao-3p, miR-4687-5p, miR-1273g-3p, miR-877-3p, miR-4312) and the function of two miRNAs that were upregulated (miR-520f-3p, miR-4307) remain unknown. [score:7]
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3
[+] score: 7
Other miRNAs from this paper: hsa-mir-1-2, hsa-mir-1-1
In addition, the authors found that a miRNA acting as a tumor suppressor, miR-4484, is deleted in GBM, thereby leading to deregulation of a panel of genes involved in various cancer-related processes [12]. [score:4]
Nawaz Z. Patil V. Thinagararjan S. Rao S. A. Hegde A. S. Arivazhagan A. Santosh V. Somasundaram K. Impact of somatic copy number alterations on the glioblastoma miRNome: miR-4484 is a genomically deleted tumour suppressorMol. [score:3]
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4
[+] score: 5
Das et al. (2013) analyzed global changes in the miRNA expression profile using microarrays and found that nine miRNA genes (miR-30a, miR-30e, miR-155, miR-1275, miR-3665, miR-3178, miR-4484, miR-4668-5p, and miR-4497) were differentially expressed in THP-1 cells infected with Mtb H37Rv or Mtb H37Ra strains. [score:5]
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5
[+] score: 4
Deregulation of a number of miRNAs in our study have been previously reported in right and left atrial appendages of patients with rheumatic mitral valve disease (RMVD), including miR-222-3p, miR-4484 and miR-940 in left atrial appendage [41], miR-5190 and miR-23c in right atrial appendages [42] and miR-143-3p in both, in the LAA and RAA of patients with RMVD [43]. [score:4]
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6
[+] score: 1
The comprehensive set of serum miRNAs (miR-1246, miR-20a, miR-2392, miR-3147, miR-3162-5p and miR-4484) have great potential to serve as potential biomarkers for LNM in early-stage squamous cell carcinoma, with an AUC of 0.992, a sensitivity of 0.967 and a specificity of 0.950 [22]. [score:1]
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7
[+] score: 1
The analysis showed that only four miRNAs: hsa-miR-4461, hsa-miR-4463, hsa-miR-4484 and hsa-miR-4485 aligned to mitochondrial genome at positions (10690–10712), (13050–13068), (5749–5766) and (2562–2582) corresponding to ND4L, ND5, L-ORF and 16S rRNA genes respectively. [score:1]
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8
[+] score: 1
They identified 6 serum miRNAs that can predict LNM in cervical SCC patients: miR-1246, miR-20a, miR-2392, miR-3147, miR-3162-5p and miR-4484. [score:1]
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