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7 publications mentioning hsa-mir-642b

Open access articles that are associated with the species Homo sapiens and mention the gene name mir-642b. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 22
Although expressed at lower levels than the highly abundant miR-30 family, two members of the miR-642 family were the most highly up-regulated miRNA in our adipogenesis mo del. [score:6]
As shown in Additional file 8, miR-642b is, in fact, located on the opposite strand to miR-642a. [score:1]
The current mirBase release (release 17) includes two miR-642 entries: miR-642a (miR-642a-5p), which was detected at one copy in a unique, high-throughput sequencing experiment; and miR-642b, which is backed by an unknown number of reads. [score:1]
This observation raises doubts about the bona fide existence of miR-642b. [score:1]
Light grey shading highlights miR-642-5p (bases in orange) and miR-642-3p (bases in blue). [score:1]
Figure S6 in Additional file 9 shows that the positions allowing discrimination of miR-642-3p from miR-642b correspond to high quality values. [score:1]
Bases that allow discrimination between miR-642-3p and miR-642b are highlighted in blue and indicated by arrows. [score:1]
While we also detected miR-642b, this sequence was much less (14-fold) abundant than miR-642a-3p. [score:1]
The mature sequence annotated in mirBase for miR-642b is the 3p arm of the pre-miRNA. [score:1]
Table S4: miR-642 raw read numbers. [score:1]
These values suggest that the corresponding reads were correctly assigned to miR-642-3p. [score:1]
In our dataset, the few reads that were attributed to miR-642b could, in fact, correspond to miR-642a-3p reads bearing sequencing errors. [score:1]
AD8, adipogenesis day 8. Figure S6: Quality values according to base position along miR-642-3p reads. [score:1]
Table S3: miR-642 family identifiers, genomic coordinates and mature sequences. [score:1]
miR-642a-3p and miR-642b sequences are, in fact, quite similar and only diverge by one base in their 3' end. [score:1]
To support this hypothesis, we counted the reads attributed to each miR-642 species within the raw read files. [score:1]
Yet, until recently (September 2010), only miR-642a-5p was present in mirBase release 15 (named miR-642 in release 15) and, thus, detectable on commercial microarrays. [score:1]
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2
[+] score: 5
For comprehensiveness, it should also be noted that analysis of the data for gender -driven differences showed that there is a significantly higher expression of hsa-miR-10b and hsa-miR-642 in males compared to females. [score:2]
This analysis included miR-184, miR-548a-5p, miR-574-3p, miR-616, miR-1233, miR-642, miR-140-3p, miR-517b, miR-10b and miR-380-3p (Figure  3, Tables  3 and 4 and Additional file 3: Table S3). [score:1]
Based on the analysis of hsa-miR-642, the population of 100 healthy subjects clearly can be separated in 2 groups, one with relatively high levels of hsa-miR-642 and one with low or undetectable levels of hsa-miR-642. [score:1]
As it has been shown that hsa-miR-642 is an adipocyte-specific miRNA, it will be of interest to see whether this hsa-miR-642 based clustering is linked to specific metabolic parameters, such as Body Mass Index or blood cholesterol and fatty acids levels, or insulin resistance [38]. [score:1]
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3
[+] score: 4
Other miRNAs from this paper: hsa-mir-29a, hsa-mir-101-1, hsa-mir-139, hsa-mir-218-1, hsa-mir-218-2, hsa-mir-142, hsa-mir-144, hsa-mir-127, hsa-mir-154, hsa-mir-185, hsa-mir-195, hsa-mir-29c, hsa-mir-101-2, hsa-mir-380, hsa-mir-381, hsa-mir-323a, hsa-mir-520e, hsa-mir-520a, hsa-mir-518c, hsa-mir-520d, hsa-mir-518a-1, hsa-mir-518d, hsa-mir-518a-2, hsa-mir-519a-1, hsa-mir-519a-2, hsa-mir-513a-1, hsa-mir-513a-2, hsa-mir-509-1, hsa-mir-576, hsa-mir-548a-1, hsa-mir-586, hsa-mir-548b, hsa-mir-548a-2, hsa-mir-599, hsa-mir-548a-3, hsa-mir-607, hsa-mir-613, hsa-mir-548c, hsa-mir-625, hsa-mir-634, hsa-mir-642a, hsa-mir-548d-1, hsa-mir-548d-2, hsa-mir-656, hsa-mir-509-2, hsa-mir-509-3, hsa-mir-1208, hsa-mir-548e, hsa-mir-548j, hsa-mir-1290, hsa-mir-548k, hsa-mir-548l, hsa-mir-548f-1, hsa-mir-548f-2, hsa-mir-548f-3, hsa-mir-548f-4, hsa-mir-548f-5, hsa-mir-1247, hsa-mir-548g, hsa-mir-548n, hsa-mir-548m, hsa-mir-548o, hsa-mir-548h-1, hsa-mir-548h-2, hsa-mir-548h-3, hsa-mir-548h-4, hsa-mir-548p, hsa-mir-548i-1, hsa-mir-548i-2, hsa-mir-548i-3, hsa-mir-548i-4, hsa-mir-1324, hsa-mir-1825, hsa-mir-548q, hsa-mir-548s, hsa-mir-548t, hsa-mir-548u, hsa-mir-548v, hsa-mir-323b, hsa-mir-548w, hsa-mir-548x, hsa-mir-548y, hsa-mir-548z, hsa-mir-548aa-1, hsa-mir-548aa-2, hsa-mir-548o-2, hsa-mir-548h-5, hsa-mir-548ab, hsa-mir-548ac, hsa-mir-548ad, hsa-mir-548ae-1, hsa-mir-548ae-2, hsa-mir-548ag-1, hsa-mir-548ag-2, hsa-mir-548ah, hsa-mir-548ai, hsa-mir-548aj-1, hsa-mir-548aj-2, hsa-mir-548x-2, hsa-mir-548ak, hsa-mir-548al, hsa-mir-548am, hsa-mir-548an, hsa-mir-548ao, hsa-mir-548ap, hsa-mir-548aq, hsa-mir-548ar, hsa-mir-548as, hsa-mir-548at, hsa-mir-548au, hsa-mir-548av, hsa-mir-548aw, hsa-mir-548ax, hsa-mir-548ay, hsa-mir-548az, hsa-mir-548ba, hsa-mir-548bb, hsa-mir-548bc
Indeed, although CTNNA2 can be regulated by primate-specific miRNAs common to both monkeys and humans (miR-513a-3p, miR-518a-5p, miR-548a-5p, miR-576-5p, miR-586, miR-607, miR-625, miR-642), a number of miRNAs present in Homo sapiens but not in Macaca mulatta (miR-1208, miR-1247, miR-1290, miR-1324, miR-1825, miR-613 and miR-634) also target CTNNA2 [19], [29]. [score:4]
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4
[+] score: 4
Epis M. R. Giles K. M. Kalinowski F. C. Barker A. Cohen R. J. Leedman P. J. Regulation of expression of deoxyhypusine hydroxylase (DOHH), the enzyme that catalyzes the activation of eIF5A, by miR-331–3p and miR-642–5p in prostate cancer cell J. Biol. [score:4]
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5
[+] score: 2
Plasma miR-22-3p, miR-642b-3p, and miR-885-5p were also shown to have high sensitivity in the diagnosis of early stage PDA together with CA19-9 [112]. [score:1]
Hussein N. A. Kholy Z. A. Anwar M. M. Ahmad M. A. Ahmad S. M. Plasma miR-22-3p, miR-642b-3p and miR-885-5p as diagnostic biomarkers for pancreatic cancer J. Cancer Res. [score:1]
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6
[+] score: 1
It was then discovered that Linc00974 acts a sponge for miR-642 that has been shown to repress KRT19 levels. [score:1]
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7
[+] score: 1
Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-let-7b, hsa-let-7e, hsa-mir-15a, hsa-mir-16-1, hsa-mir-17, hsa-mir-18a, hsa-mir-19a, hsa-mir-19b-1, hsa-mir-19b-2, hsa-mir-20a, hsa-mir-21, hsa-mir-22, hsa-mir-23a, hsa-mir-24-1, hsa-mir-24-2, hsa-mir-25, hsa-mir-27a, hsa-mir-30a, hsa-mir-92a-1, hsa-mir-92a-2, hsa-mir-99a, hsa-mir-100, hsa-mir-101-1, hsa-mir-103a-2, hsa-mir-103a-1, hsa-mir-106a, hsa-mir-16-2, hsa-mir-192, hsa-mir-196a-1, hsa-mir-199a-1, hsa-mir-148a, hsa-mir-10a, hsa-mir-196a-2, hsa-mir-199a-2, hsa-mir-203a, hsa-mir-215, hsa-mir-221, hsa-mir-222, hsa-mir-223, hsa-mir-200b, hsa-mir-1-2, hsa-mir-15b, hsa-mir-27b, hsa-mir-122, hsa-mir-125b-1, hsa-mir-133a-1, hsa-mir-133a-2, hsa-mir-141, hsa-mir-143, hsa-mir-145, hsa-mir-152, hsa-mir-191, hsa-mir-125a, hsa-mir-125b-2, hsa-mir-126, hsa-mir-127, hsa-mir-146a, hsa-mir-150, hsa-mir-185, hsa-mir-194-1, hsa-mir-195, hsa-mir-320a, hsa-mir-200c, hsa-mir-1-1, hsa-mir-155, hsa-mir-128-2, hsa-mir-194-2, hsa-mir-200a, hsa-mir-101-2, hsa-mir-130b, hsa-mir-302c, hsa-mir-375, hsa-mir-378a, hsa-mir-148b, hsa-mir-324, hsa-mir-451a, hsa-mir-483, hsa-mir-484, hsa-mir-486-1, hsa-mir-500a, hsa-mir-92b, hsa-mir-595, hsa-mir-596, hsa-mir-421, hsa-mir-378d-2, hsa-mir-744, hsa-mir-885, hsa-mir-939, hsa-mir-940, hsa-mir-1229, hsa-mir-1233-1, hsa-mir-1290, hsa-mir-1246, hsa-mir-103b-1, hsa-mir-103b-2, hsa-mir-718, hsa-mir-378b, hsa-mir-378c, hsa-mir-4306, hsa-mir-4286, hsa-mir-500b, hsa-mir-1233-2, hsa-mir-3935, hsa-mir-378d-1, hsa-mir-378e, hsa-mir-378f, hsa-mir-378g, hsa-mir-378h, hsa-mir-378i, hsa-mir-3976, hsa-mir-4644, hsa-mir-203b, hsa-mir-451b, hsa-mir-378j, hsa-mir-486-2
Several circulating miRNAs, such as miR-27a, miR-642b, miR-885-5p, miR-22, miR-21, miR-483, miR-1246, miR-4644, miR-3976, and miR-4306, have been identified as novel diagnostic markers with acceptable availability in PCa patients [70, 71, 72, 73]. [score:1]
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