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10 publications mentioning hsa-mir-3613

Open access articles that are associated with the species Homo sapiens and mention the gene name mir-3613. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 45
RT-qPCR was performed on 5 differentially expressed miRNAs (3 upregulated: miR-466, miR-574-3p, miR-3613-3p; and 2 downregulated: miR-1, miR-26a-5p) to confirm the microarray data. [score:9]
Finally, we selected 5 miRNAs for further analysis: 3 were upregulated in the AF group relative to the NSR (hsa-miR-466, hsa-miR-574-3p, and hsa-miR-3613-3p), and 2 were downregulated (hsa-miR-1 and hsa-miR-26a-5p). [score:7]
The miRNAs hsa-miR-1 and hsa-miR-26a-5p were predicted by 5 target prediction databases; hsa-miR-574-3p was predicted from 4 target prediction databases, and hsa-miR-466 and hsa-miR-3613-3P were predicted from 2 target prediction databases (Table 3). [score:7]
According to the RT-qPCR data, hsa-miR-466, hsa-miR-574-3p, and hsa-miR-3613-3p were upregulated in the LAAs of the AF group relative to the NSR, while hsa-miR-1 and hsa-miR-26a-5p were downregulated. [score:7]
To determine the probable biological function of the differentially expressed miRNAs, we predicted the putative targets and pathways of 5 validated miRNAs (hsa-miR-1, hsa-miR-26a-5p, hsa-miR-466, hsa-miR-574-3p, and hsa-miR-3613-3p) using the miRFocus database. [score:5]
Our study found that the expression levels of three validated miRNAs (miR-1, miR-26a-5p, miR-466) correlated with LA size, while those of two others (miR-574-3p, miR-3613-3p) did not. [score:3]
The expression levels of miR-574-3p and miR-3613-3p were not significantly correlated with LA size. [score:3]
However, although the expression levels of miR-574-3p and miR-3613-3p in LAAs significantly differed between NSR and AF patients, they were not significantly correlated with LA size (r = 0.54; P = 0.07 and r = 0.56; P = 0.06, respectively; Figure 6). [score:3]
Previously, the miR-466, miR-574, and miR-3613 have not been described as participating in cardiovascular pathology. [score:1]
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2
[+] score: 24
Among these AF -associated miRNAs, 22 were up-regulated and 20 were down-regulated (Table  3 and Figure  3B) Table 3 miRNA expression differences between AF-LAA and SR-LAA miRNA SR-LAA signal AF-LAA signal Log 2 (AF-LAA/SR-LAA) P -valueUp-regulated (n = 22*)hsa-miR-3613-3p29430633.381.07E-02hsa-miR-49429618812.675.89E-02hsa-miR-3591-3p53920691.947.14E-02hsa-miR-4485802841.835.03E-02hsa-miR-574-3p4478135161.592.41E-02hsa-miR-466118333431.502.31E-02hsa-miR-44923348341.322.73E-02hsa-let-7d-3p1463441.239.94E-02hsa-miR-4707-5p3878571.152.92E-02hsa-miR-4534791721.126.66E-02hsa-miR-3940-5p3978031.025.71E-02hsa-miR-31781853741.011.97E-02hsa-miR-15b-5p3837230.923.04E-02hsa-miR-21-5p4428190.894.66E-02hsa-miR-3196138324770.841.34E-02hsa-miR-1307-3p821450.835. [score:12]
Among these AF -associated miRNAs, 22 were up-regulated and 20 were down-regulated (Table  3 and Figure  3B) Table 3 miRNA expression differences between AF-LAA and SR-LAA miRNA SR-LAA signal AF-LAA signal Log 2 (AF-LAA/SR-LAA) P -valueUp-regulated (n = 22*)hsa-miR-3613-3p29430633.381.07E-02hsa-miR-49429618812.675.89E-02hsa-miR-3591-3p53920691.947.14E-02hsa-miR-4485802841.835.03E-02hsa-miR-574-3p4478135161.592.41E-02hsa-miR-466118333431.502.31E-02hsa-miR-44923348341.322.73E-02hsa-let-7d-3p1463441.239.94E-02hsa-miR-4707-5p3878571.152.92E-02hsa-miR-4534791721.126.66E-02hsa-miR-3940-5p3978031.025.71E-02hsa-miR-31781853741.011.97E-02hsa-miR-15b-5p3837230.923.04E-02hsa-miR-21-5p4428190.894.66E-02hsa-miR-3196138324770.841.34E-02hsa-miR-1307-3p821450.835. [score:12]
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3
[+] score: 13
The basal expression levels of miR-3613-3p and miR-3163 did not show any correlation with eEF2K expression in TNBC cell lines (Supplementary Figure 1B and 1C). [score:5]
The basal expression levels of miR-603, miR-3613-3p, and miR-3163 in TNBC cell lines (MDA-MB-231, MDA-MB-436, and BT-20) were compared to their expression levels in MCF-10A cells by qPCR. [score:4]
We also selected miR-3613-3p and miR-3163 that were common in the three of the databases for binding scores for targeting eEF2K (Figure 1E). [score:3]
MDA-MB-436, MDA-MB-231, and BT-20 cells were plated in six-well plates at a density of 1.5 × 10 [5] cells/well and transiently transfected with 100 nM mature mimics of miR-603, miR-3613-3p, and miR-3163 or 100 nM control miRNA (all from Ambion) by using HiPerFect transfection reagent (Qiagen) in Opti-MEM Reduced Serum Medium (Life Technologies) according to the manufacturer's protocol. [score:1]
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4
[+] score: 11
The eight miRNAs selected included the most upregulated miRNAs (miR-512-3p, miR-377-5p, miR-433-3p and miR-1323) and most downregulated miRNAs (miR-33a-5p, miR-551b-3p, miR-3613-5p and miR-144-3p) in OS. [score:7]
Among these, miR-512-3p, miR-377-5p, miR-433-3p and miR-1323 were the greatest upregulated miRNAs, whereas miR-33a-5p, miR-551b-3p, miR-3613-5p and miR-144-3p were the most decreased miRNAs in OS. [score:4]
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5
[+] score: 7
Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-let-7b, hsa-let-7c, hsa-let-7d, hsa-let-7e, hsa-let-7f-1, hsa-let-7f-2, hsa-mir-15a, hsa-mir-16-1, hsa-mir-17, hsa-mir-21, hsa-mir-24-1, hsa-mir-24-2, hsa-mir-26a-1, hsa-mir-26b, hsa-mir-27a, hsa-mir-29a, hsa-mir-30a, hsa-mir-98, hsa-mir-101-1, hsa-mir-29b-1, hsa-mir-29b-2, hsa-mir-106a, hsa-mir-107, hsa-mir-16-2, hsa-mir-198, hsa-mir-148a, hsa-mir-30d, hsa-mir-7-1, hsa-mir-7-2, hsa-mir-7-3, hsa-mir-34a, hsa-mir-181a-2, hsa-mir-181c, hsa-mir-182, hsa-mir-183, hsa-mir-205, hsa-mir-210, hsa-mir-181a-1, hsa-mir-222, hsa-mir-224, hsa-mir-200b, hsa-let-7g, hsa-let-7i, hsa-mir-23b, hsa-mir-27b, hsa-mir-124-1, hsa-mir-124-2, hsa-mir-124-3, hsa-mir-125b-1, hsa-mir-128-1, hsa-mir-132, hsa-mir-137, hsa-mir-140, hsa-mir-141, hsa-mir-142, hsa-mir-143, hsa-mir-144, hsa-mir-153-1, hsa-mir-153-2, hsa-mir-9-1, hsa-mir-9-2, hsa-mir-9-3, hsa-mir-125a, hsa-mir-125b-2, hsa-mir-126, hsa-mir-134, hsa-mir-136, hsa-mir-146a, hsa-mir-150, hsa-mir-184, hsa-mir-185, hsa-mir-186, hsa-mir-206, hsa-mir-320a, hsa-mir-200c, hsa-mir-128-2, hsa-mir-200a, hsa-mir-101-2, hsa-mir-34b, hsa-mir-34c, hsa-mir-299, hsa-mir-26a-2, hsa-mir-373, hsa-mir-376a-1, hsa-mir-342, hsa-mir-133b, hsa-mir-424, hsa-mir-429, hsa-mir-433, hsa-mir-451a, hsa-mir-146b, hsa-mir-494, hsa-mir-193b, hsa-mir-455, hsa-mir-376a-2, hsa-mir-33b, hsa-mir-644a, hsa-mir-548d-1, hsa-mir-548d-2, hsa-mir-320b-1, hsa-mir-320c-1, hsa-mir-320b-2, hsa-mir-301b, hsa-mir-320d-1, hsa-mir-320c-2, hsa-mir-320d-2, hsa-mir-320e, hsa-mir-4668, hsa-mir-4674, hsa-mir-6722
Kumar et al. (2017) demonstrated that upregulation of miRNA-455-3p, miRNA-4668-5p, miRNA-3613-3p, and miRNA-4674, while downregulation of miRNA-6722 in 10 AD positive brain samples. [score:7]
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6
[+] score: 1
48E-051.589 rs12178 ZBTB34 0.456 hsa-miR-1267, hsa-miR-501-5p, hsa-miR-3613-3p, hsa-miR-653 A/C/G/T rs12178 1 9.66E-05 1.277 Eleven putative miRNA-related SNPs link to SCZ-GWAS SNPs with a significance of p < 0.0001. [score:1]
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7
[+] score: 1
In a number of cases we found miRNA* sequences to be dominant strand in A33-Exos (miR-3613-3p*, -362-3p*, -625-3p*, -6842-3p*) to that which was dominant in the parent LIM1863 cells (Figure 4B ). [score:1]
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8
[+] score: 1
Other miRNAs from this paper: hsa-mir-106b, hsa-mir-151a, hsa-mir-1229
In addition, hsa-miR-3613-3p was found to be undetectable in the sample groups in qPCR analysis. [score:1]
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9
[+] score: 1
Most of the hypomethylated miRNAs lacked a CGI in their promoters; aberrant methylation was located on the CGI shores of several miRNA promoters, such as hsa-mir-106a, hsa-mir-1292 and hsa-mir-3613. [score:1]
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10
[+] score: 1
GeneGene-level p-value [a] GS GS p-value MM MM p-valueRank [b] miRNA r [c] p-value FDR GPD1L 2.67E-02 −0.23 1.06E-03 0.90 1.29E-71 1 hsa-miR-210 −0.17 7.37E-03 7.91E-02 CCDC50 2.12E-02 −0.20 4.68E-03 0.85 6.79E-58 2 hsa-miR-501-3p −0.19 3.93E-03 5.05E-02 NAALAD2 8.05E-03 −0.24 5.76E-04 0.85 1.47E-57 3 hsa-miR-140-3p −0.29 1.97E-05 7.98E-04 ALDH1L1 4.94E-03 −0.28 7.13E-05 0.85 3.15E-57 4 hsa-miR-342-5p −0.27 5.13E-05 1. 76E-03 ADH1B 3.14E-02 −0.27 8.82E-05 0.85 4.39E-56 5 — — — — ADH1A 5.00E-02 −0.26 1.83E-04 0.82 2.34E-50 6 hsa-miR-590-3p −0.09 1.06E-01 4.46E-01 PCCA 2.38E-02 −0.21 2.68E-03 0.82 3.87E-49 8 hsa-miR-301b −0.25 2.08E-04 5.42E-03 ORMDL3 3.87E-03 −0.29 3.04E-05 0.80 3.29E-45 9 hsa-miR-362-3p −0.20 2.12E-03 3.23E-02EPB41L4B [d] 7.42E-05 −0.29 3. 47E-05 0.67 2.63E-27 28 has-miR-3613-3p −0.11 6.46E-02 3.4E-01GS, gene significance; MM, module membership. [score:1]
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