sort by

1 publications mentioning rno-mir-3586

Open access articles that are associated with the species Rattus norvegicus and mention the gene name mir-3586. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 12
Other miRNAs from this paper: rno-mir-30c-2, rno-mir-144, rno-mir-146b, rno-mir-486
The primers used for the miRNAs expression analysis are shown in Table  4. The real time quantitative PCR results indicated that the expression levels of rno-miR-30c-2-3p, rno-miR-486 or rno-miR-3586-3p were significantly higher in the (Fig.   8a– d), while Heqi San or MET treatment could decreased the expression levels of all three miRNAs when compared with the untreated PCOS group (Fig. 8a– d). [score:5]
Heqi: Heqi San, MET: metformin We then used the bioinformatics analysis to identify certain differences in miRNA between the control group and PCOS groups, and some of the identified miRNAs involved in the P13K/AKT pathway are listed in Table  3. Accordingly, we selected four miRNAs (rno-miR-30c-2-3p, rno-miR-146b-5p, rno-miR-486 and rno-miR-3586-3p) and determined their expression levels in the different groups. [score:3]
Heqi: Heqi San, MET: metformin We then used the bioinformatics analysis to identify certain differences in miRNA between the control group and PCOS groups, and some of the identified miRNAs involved in the P13K/AKT pathway are listed in Table  3. Accordingly, we selected four miRNAs (rno-miR-30c-2-3p, rno-miR-146b-5p, rno-miR-486 and rno-miR-3586-3p) and determined their expression levels in the different groups. [score:3]
Through a bioinformatical analysis, we predicted the related gene function and pathway of the pathological mechanism of PCOS and found miRNAs that are likely to be critical in PCOS occurrence, including rno-miR-144-3p, rno-miR-30c-2-3p, rno-miR-486, rno-miR-3586-3p and rno-miR-146b-5p. [score:1]
[1 to 20 of 4 sentences]