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1 publications mentioning rno-mir-3560

Open access articles that are associated with the species Rattus norvegicus and mention the gene name mir-3560. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

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[+] score: 18
Thermo-sensitive miRNAs Fold change in miRNA Fold change in target mRNA Predicted gene targets Cell Type rno-miR-22-3P + 3.4 −13.5 Acly Spermatid rno-miR-22-5P + 1.8 −13.5 Acly Spermatid rno-miR-129-5P −1.9 + 8.5 selV Spermatocyte rno-miR-3560 + 2.1 −1.6 MCT2 Spermatocyte rno-miR-3560 + 2.1 −12.3 Txnrd1 Spermatocyte rno-miR-466c-5P + 1.5 −1.8 Prkar2B Spermatid Crytorchidism is a state wherein the loss of germ cells takes place by apoptosis leading to infertility, and transient testicular heating has been shown to provide reversible contraception in men [25] and temporary sterility in rats [26]. [score:5]
Thermo-sensitive miRNAs Fold change in miRNA Fold change in target mRNA Predicted gene targets Cell Type rno-miR-22-3P + 3.4 −13.5 Acly Spermatid rno-miR-22-5P + 1.8 −13.5 Acly Spermatid rno-miR-129-5P −1.9 + 8.5 selV Spermatocyte rno-miR-3560 + 2.1 −1.6 MCT2 Spermatocyte rno-miR-3560 + 2.1 −12.3 Txnrd1 Spermatocyte rno-miR-466c-5P + 1.5 −1.8 Prkar2B Spermatid The H & E stained testes sections of control and cryptorchid rat suggest that at 24 h there was negligible visible change in any stage of spermatogenesis and most of the stages were present (Fig.   1b), as in control (Fig. 1a). [score:5]
The study has identified Acly, selV, SLC16A7(MCT-2), Txnrd1 and Prkar2B as potential heat sensitive targets in germ cells, which may be tightly regulated by heat sensitive miRNAs rno-miR-22-3P, rno-miR-22-5P, rno-miR-129-5P, rno-miR-3560, rno-miR-3560 and rno-miR-466c-5P. [score:4]
Among various pathways affected significantly by heat stress, the study has identified Acly, selV, SLC16A7(MCT-2), Txnrd1 and Prkar2B as potential heat sensitive targets in germ cells, which may be under tight regulation of heat sensitive miRNAs, rno-miR-22-3P, rno-miR-22-5P, rno-miR-129-5P, rno-miR-3560, rno-miR-3560 and rno-miR-466c-5P, as predicted by miRDB tool. [score:4]
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