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6 publications mentioning hsa-mir-3151

Open access articles that are associated with the species Homo sapiens and mention the gene name mir-3151. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

[+] score: 21
Other miRNAs from this paper: hsa-mir-181a-2, hsa-mir-181a-1
Expression of human U6 snRNA was used to normalized miRNA181a and miRNA3151 gene expression in qRT-PCR. [score:5]
ERG and MLL mutations, and higher miR-3151 expression level showed a trend of adverse impact on survival. [score:4]
There are no different of NPM1, FLT3-ITD, IDH1/2, DNMT3A and MLL gene mutations, and no difference in BDH2, ERG, MN1, miR-181a and miR-3151 expression levels, between different age group. [score:4]
ANOVA were used to analyze ERG, NM1, miR-181a and miR-3151 in different groups of BDH2 expression and age. [score:3]
Quantitative real-time reverse transcriptase-polymerase chain reaction (qRT-PCR) for mRNA expression analysis of BDH2, LCN2, Meningionma1 (MN1), ETS-related gene (ERG), micro -RNA-181a (miR-181a), and micro -RNA-3151 (miR-3151). [score:3]
BDH2: Type 2-hydroxybutyrate dehydrogenase; LCN2: Lipocalin-2; CEBPA: CCAAT/enhancer binding protein (C/EBP), alpha; FLT3-ITD: Fms-related tyrosine kinase 3 Internal tandem duplications; NPM1: Nucleophosmin 1; IDH1/2: Isocitrate dehydrogenase 1/2; DNMT3A: DNA (cytosine-5)-methyltransferase 3A; MLL: Mixed lineage leukemia gene; MN1: Meningionma1; ERG: ETS-related gene; miR-181a: Micro -RNA-181a; miR-3151: Micro -RNA-3151; CR: Complete remission; OS: Overall survival; RFS: Relapse free survival; LFS: Leukemia free survival. [score:1]
641%)2 (4.88%) 0.009* MLL [b]7 (8.75%)3 (7.69%)4 (9.76%) 0.426 ERG [c]11.17 (10.26-12.08)11.60 (10.48-12.72)10.68 (9.17-12.20) 0.320 MN1 [c]12.98 (12.28-13.68)13.35 (12.42-14.28)12.55 (11.47-13.64) 0.257 miR-181a [c]3.12 (2.57-3.67)3.17 (2.35-3. 98)3.07 (2.30-3.84) 0.864 miR-3151 [c] 12.35 (11.90-12.80) 12.18 (11.53-12.84) 12.53 (11.89-13.16) 0.448 Values are number (%) of patients with alteration. [score:1]
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[+] score: 19
Similar results were observed in p53 [+/+] and p53 [−/−] cells (Figure 2c): the expression levels of miR-3151 and miR-663b were upregulated in p53 [−/−] cells, while the expression levels of miR-140, miR-30b, miR-506, miR-124 and miR-30c were downregulated in p53 [−/−] cells compared with that in p53 [+/+] cells. [score:10]
In p53 [mut] cell line HT29, the expression levels were significantly downregulated except miR-3151 and miR-663b (which were significantly upregulated), compared with p53 [wt] cell line R KO (Figure 2b). [score:8]
Several miRNAs were proposed, among which seven of them were reported to be related to p53: miR-140, miR-30b, miR-3151, miR-506, miR-124, miR-30c, and miR-663b 19, 20, 21, 22, 23, 24 (Figure 2a). [score:1]
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[+] score: 17
Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-let-7b, hsa-let-7c, hsa-let-7d, hsa-let-7e, hsa-let-7f-1, hsa-let-7f-2, hsa-mir-15a, hsa-mir-16-1, hsa-mir-17, hsa-mir-18a, hsa-mir-19a, hsa-mir-19b-1, hsa-mir-19b-2, hsa-mir-20a, hsa-mir-21, hsa-mir-23a, hsa-mir-25, hsa-mir-26a-1, hsa-mir-27a, hsa-mir-29a, hsa-mir-30a, hsa-mir-31, hsa-mir-33a, hsa-mir-92a-1, hsa-mir-92a-2, hsa-mir-93, hsa-mir-96, hsa-mir-99a, hsa-mir-100, hsa-mir-29b-1, hsa-mir-29b-2, hsa-mir-16-2, hsa-mir-198, hsa-mir-199a-1, hsa-mir-148a, hsa-mir-7-1, hsa-mir-7-2, hsa-mir-7-3, hsa-mir-10a, hsa-mir-10b, hsa-mir-34a, hsa-mir-181a-2, hsa-mir-181b-1, hsa-mir-181c, hsa-mir-182, hsa-mir-199a-2, hsa-mir-199b, hsa-mir-203a, hsa-mir-204, hsa-mir-210, hsa-mir-212, hsa-mir-181a-1, hsa-mir-214, hsa-mir-215, hsa-mir-216a, hsa-mir-217, hsa-mir-218-1, hsa-mir-218-2, hsa-mir-219a-1, hsa-mir-221, hsa-mir-222, hsa-mir-223, hsa-mir-224, hsa-let-7g, hsa-let-7i, hsa-mir-15b, hsa-mir-27b, hsa-mir-124-1, hsa-mir-124-2, hsa-mir-124-3, hsa-mir-125b-1, hsa-mir-128-1, hsa-mir-130a, hsa-mir-132, hsa-mir-135a-1, hsa-mir-135a-2, hsa-mir-142, hsa-mir-145, hsa-mir-191, hsa-mir-9-1, hsa-mir-9-2, hsa-mir-9-3, hsa-mir-125a, hsa-mir-125b-2, hsa-mir-126, hsa-mir-134, hsa-mir-146a, hsa-mir-150, hsa-mir-186, hsa-mir-188, hsa-mir-193a, hsa-mir-194-1, hsa-mir-320a, hsa-mir-155, hsa-mir-181b-2, hsa-mir-128-2, hsa-mir-194-2, hsa-mir-106b, hsa-mir-29c, hsa-mir-219a-2, hsa-mir-34b, hsa-mir-34c, hsa-mir-99b, hsa-mir-130b, hsa-mir-30e, hsa-mir-26a-2, hsa-mir-362, hsa-mir-369, hsa-mir-375, hsa-mir-378a, hsa-mir-382, hsa-mir-340, hsa-mir-328, hsa-mir-342, hsa-mir-151a, hsa-mir-148b, hsa-mir-331, hsa-mir-339, hsa-mir-335, hsa-mir-345, hsa-mir-196b, hsa-mir-424, hsa-mir-425, hsa-mir-20b, hsa-mir-451a, hsa-mir-409, hsa-mir-484, hsa-mir-486-1, hsa-mir-487a, hsa-mir-511, hsa-mir-146b, hsa-mir-496, hsa-mir-181d, hsa-mir-523, hsa-mir-518d, hsa-mir-499a, hsa-mir-501, hsa-mir-532, hsa-mir-487b, hsa-mir-551a, hsa-mir-92b, hsa-mir-572, hsa-mir-580, hsa-mir-550a-1, hsa-mir-550a-2, hsa-mir-590, hsa-mir-599, hsa-mir-612, hsa-mir-624, hsa-mir-625, hsa-mir-627, hsa-mir-629, hsa-mir-33b, hsa-mir-633, hsa-mir-638, hsa-mir-644a, hsa-mir-650, hsa-mir-548d-1, hsa-mir-449b, hsa-mir-550a-3, hsa-mir-151b, hsa-mir-320b-1, hsa-mir-320c-1, hsa-mir-454, hsa-mir-320b-2, hsa-mir-378d-2, hsa-mir-708, hsa-mir-216b, hsa-mir-1290, hsa-mir-320d-1, hsa-mir-320c-2, hsa-mir-320d-2, hsa-mir-378b, hsa-mir-320e, hsa-mir-378c, hsa-mir-550b-1, hsa-mir-550b-2, hsa-mir-378d-1, hsa-mir-378e, hsa-mir-378f, hsa-mir-378g, hsa-mir-378h, hsa-mir-378i, hsa-mir-219b, hsa-mir-203b, hsa-mir-451b, hsa-mir-499b, hsa-mir-378j, hsa-mir-486-2
High expression of miR-3151 was associated with a low expression of genes involved in transcriptional regulation, posttranslational modification, and cancer pathways, such as FBXL20 and USP40 [130]. [score:8]
High miR-3151 expression was associated with high miR-501-5p and low miR-590, miR-135a, miR-100*, miR-186* and let-7a* expression, however the significance of this association is unknown [129]. [score:5]
Up-regulated miR-3151 was found in AML patients with an unfavorable prognosis, such as short overall survival and leukemia-free survival, and higher relapse risk [129, 130]. [score:4]
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[+] score: 12
In 179 CN-AML patients over 60 years of age high miR-3151 expression was associated with shorter disease-free and overall survival; high expressing patients also had a lower CR rate compared with low expressers. [score:8]
In other work, patients with increased miR-3151 had shorter overall and leukemia-free survival and higher cumulative incidence of relapse [95]. [score:1]
It was reported that patients with low levels of both miR-3151 and BAALC had better outcomes than patients with increased levels of either marker [95]. [score:1]
Moreover, multivariate analysis demonstrated that the combined observation of miR-3151 and its host gene BAALC improved this prognostic stratification. [score:1]
Eisfeld et al reported miR-3151 as an independent prognostic factor for outcome in older CN-AML patients [94]. [score:1]
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[+] score: 12
The two genes impact on different outcome endpoints: high miR-3151 expression associated with shorter disease-free and overall survival, while high BAALC expression predicted failure of complete remission and shorter overall survival [111]. [score:7]
Recently, high expression of miR-3151 was discovered an independent prognostic marker for poor outcome in CN-AML [111]. [score:3]
MiR-3151 is encoded in an intron of the coding gene BAALC, which also associate with poor outcome when highly expressed in CN-AML [112]. [score:2]
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[+] score: 1
Top three of them were positions 87 of hsa-miR-3151 and hsa-miR-4259, 1331 of hsa-miR-611, and 1478 of hsa-miR-1236. [score:1]
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