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4 publications mentioning mmu-mir-1251

Open access articles that are associated with the species Mus musculus and mention the gene name mir-1251. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

[+] score: 11
The downregulation of miR-1251-5p and miR-34a-5p might alleviate cognitive deficit by increasing the activity of disintegrin and metalloprotease 10 (ADAM10), a major α-secretase in brain that is capable of attenuating the production of A β by cleavage of APP, resulting in soluble APP α [27]. [score:4]
MiR-342-5p, miR-3058-3p, let-7f-5p, miR-1961, miR-301b-3p, miR-98-5p, miR-1251-5p, miR-215-5p, miR-881-5p, miR-135a-2-3p, and miR-33-3p may regulate the expression of insulin-like growth factor 1 (IGF1) or insulin-like growth factor 2 (IGF2), two molecules that could rescue behavior and memory deficits via lowering A β levels [28, 29]. [score:4]
Several miRNAs derived from our microarray analysis targeted PTEN, such as miR-376c-3p, miR-342-3p, let-7f-5p, miR-10a-5p, miR-301b-3p, miR-98-5p, miR-1251-5p, and miR-34a-5p. [score:3]
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[+] score: 2
Among these, insulin-like growth factor 1 gene (IGF1) was under positive regulation by androgens through miR-215 on GD 17.0, and through miR-30e, miR-1251, miR-709, miR-344f-3p, and miR-466l-5p on GD 18.0. [score:2]
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[+] score: 1
Several editing events within the seed were found to be much more ancient than previously recognized: editing of miR-27a was found in placental mammals and platypus, thus presumably dating back at least 220 million years, while editing of miR-187*, miR-497 and miR-1251 was shared between placental mammals and marsupials, whose last common ancestor lived 180 million years ago [20]. [score:1]
[1 to 20 of 1 sentences]
[+] score: 1
Other miRNAs from this paper: hsa-mir-1251
Two miRNAs (eutherian-conserved MIR1251 and vertebrate-conserved MIR135A2) are embedded in introns of Rmst alternative splice variants, indicating that this lncRNA might function as a miRNA host transcript. [score:1]
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