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5 publications mentioning eca-let-7d

Open access articles that are associated with the species Equus caballus and mention the gene name let-7d. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 17
In total 1077 of the predicted targets were unique to these 2 miRNAs while only 3 gene targets were predicted for let-7d-3p. [score:5]
Expression of let-7d-3p and let-7d-5p decreased 0.68 ± 0.1 and 0.44 ± 0.1 fold, respectively. [score:3]
In the present study, two members of the let-7 family of miRNAs, let-7d-3p and let-7d-5p, and miR-21-5p had increased expression following exercise. [score:3]
In skeletal muscle samples, 97/179 miRNAs were detected with 5 miRNAs (miR-21-5p, let-7d-3p, let-7d-5p, miR-30b-5p, miR-30e-5p) differentially expressed (DE, P < 0.05) between time-points. [score:3]
The Let-7 family of miRNAs are involved in the regulation of glucose homeostasis and insulin sensitivity [43], both key processes in energy metabolism during exercise. [score:2]
Accession numbers for the miRNA data generated in this study are: MIMAT0004484 (hsa-let-7d-3p), MIMAT0000076 (hsa-miR-21-5p), MIMAT0000065 (hsa-let-7d-5p), MIMAT0000420 (hsa-miR-30b-5p) and MIMAT0000692 (hsa-miR-30e-5p). [score:1]
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2
[+] score: 5
It inhibits the processing of microRNAs (miRNAs) into mature miRNAs by binding to the terminal loops of miRNA precursors such as let-7 family members [6]. [score:3]
The let-7 family of microRNAs. [score:1]
Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing. [score:1]
[1 to 20 of 3 sentences]
3
[+] score: 5
Koh W. Sheng C. T. Tan B. Lee Q. Y. Kuznetsov V. Kiang L. S. Tanavde V. Analysis of deep sequencing microRNA expression profile from human embryonic stem cells derived mesenchymal stem cells reveals possible role of let-7 microRNA family in downstream targeting of hepatic nuclear factor 4 alphaBMC Genom. [score:5]
[1 to 20 of 1 sentences]
4
[+] score: 2
The discovery of the regulatory miRNA let-7 in C. elegans in 2000 [10], with homologs in other species including humans, caused researchers to reconsider the idea that miRNAs may have a more widespread function within cells. [score:2]
[1 to 20 of 1 sentences]
5
[+] score: 1
This suggests that the 10 most abundant plasma miRNA species did not belong to the abundant miRNA group in non-plasma tissues, except for the eca-let-7 family species (S4 Table). [score:1]
[1 to 20 of 1 sentences]