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3 publications mentioning hsa-mir-1287

Open access articles that are associated with the species Homo sapiens and mention the gene name mir-1287. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 22
We found that miR-432, miR-1286, miR-641, miR-1290, miR-1287 and miR-95 were highly upregulated just in cells with HPV infection upon 5-AZA treatment, whereas miR-625 was significantly downregulated (P<0.05) (Figure  3). [score:7]
Most of these miRNAs were significantly down-regulated in tumor samples, but miR-1287 was consistently expressed in tumor tissues and serum samples (Guo L, et al., [18]). [score:6]
Interestingly, expression of miR-641 and miR-1287 in cervical tissue was lower than control, while miR-95 was higher (P<0.05). [score:3]
Our study found that the contents of promoter methylation in miR-641 and miR-1287 were inversely correlated with the expression levels of these genes in cells treated with 5-aza-2’-deoxycytidine. [score:3]
MiR-432, miR-1286, miR-641, miR-1290, miR-1287 and miR-95 were found up-modulated in Caski, Hela and Siha but not in C33A induced on treatment, while miR-625 was down-modulated. [score:1]
MiR-641, miR-1287 and miR-95 changing most significantly in cell lines were chosen for further study in cervical tissue. [score:1]
We found hypermethylation of miR-432, miR-1286, miR-641, miR-1290, miR-1287 and miR-95 may have some relationship with HPV infection in cervical cell lines. [score:1]
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2
[+] score: 9
The demographics and standard clinical chemistry for this patient cohort are presented in supplementary Table 4. In accordance with the NormFinder assessment, miR-1287 was most stably expressed across the different samples with a coefficient of variation (CV) of 1.71% (supplementary Figure 2). [score:3]
miR-1287 was the most stably expressed with a stability value of 1.22*10−5. [score:3]
Values represent 2 [−ΔCt] normalised by miR-1287 in human samples and spiked in synthetic miR-39 in mice samples. [score:1]
The miRNAs are normalized by miR-1287. [score:1]
In the 67 APAP-early patients, miR-122-5p identified subsequent liver injury when normalized by any of the 6 endogenous miRNA normalizers described above (miR-122-5p area under ROC curve normalized by miR-1913, 0.97 (95% CI 0.92–1.01); miR-671, 0.96 (0.92–1.01); miR-1287, 0.95 (0.90–1.00); let7-d, 0.94 (0.89–1.00); miR-1260, 0.93 (0.88–1.00); miR-324, 0.93 (0.87–1.00) miR-122-5p ROC-AUC significantly larger than all other miRNAs – P < 0.05). [score:1]
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3
[+] score: 4
Locus ID Gene RefSeq Expression Phastcons Status 21019 Intron - AC124066.2 1,12,2,1 0.57 miR-1180 38843 Intron ARL10 - 0,0,3,2 0.99 miR-1271 6150 Intron C10orf33 - 4,0,1,4 1 miR-1287 6746 Intron JMJD1C - 1,4,2,1 1 miR-1296 27738 Intron DNMT3A - 3,12,7,4 0.99 miR-1301 8884 intron FADS1 NM_013402 2,0,9,2 0.34 miR-1908 37600 repeat - - 136,933,146,220 0.03 alt. [score:3]
While writing this paper a new version of miRBase was released, now including six of these miRNAs (mir-1180, mir-1271, mir-1287, mir-1296, mir-1301, and mir-1908). [score:1]
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