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4 publications mentioning rno-mir-743b

Open access articles that are associated with the species Rattus norvegicus and mention the gene name mir-743b. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

[+] score: 30
Rather in intestines, we detected significant downregulation of miR-743b in rats with aGvHD disease and a trend toward decreased expression of miR-345-5p. [score:8]
Here, miR-125a-5p, miR-326, miR-345-5p, and miR-743b were downregulated in both intestinal tissue and intestinal T cells, while miR-17-1-3p, miR-290, and miR-3548 were upregulated (Figure 6E). [score:7]
Specifically, upregulation of miR-466b (1.99-fold change, p = 0.017), miR-542-5p (3.09-fold change, p = 0.020), miR-568 (2.14-fold change, p = 0.020), miR-3580-3p (1.99-fold change, p = 0.017), miR-3581 (1.79-fold change, p = 0.019), and miR-3597-5p (1.9-fold change, p = 0.037), and downregulation of miR-345-5p (−1.56-fold change, p = 0.006) and miR-743b (−2.74-fold change, p = 0.031) were detected for aGvHD samples compared to controls (Figures 5A,B). [score:6]
Quantitative RT-PCR validation of samples obtained from the same and another independent transplantation experiment confirmed downregulation of miR-743b (Figure 5C). [score:4]
Lastly, a comparison of intestinal tissue with intestinal T cells from aGvHD rats showed that only miR-743b were significantly differentially expressed (Figure 6F). [score:3]
miR-99a, miR-345-5p, or miR-743b was not found associated with any of the other miRNAs or to genes related to T cell activation. [score:1]
As input for the analysis, we chose miR-21, miR-99a, miR-223, miR-326, miR-345-5p, and miR-743b, and also genes involved in GvHD pathogenesis as well as T cell activation, proliferation, and migration. [score:1]
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[+] score: 10
Several miRNAs, such as members of the miR-183-96-182 cluster, miR-741, miR-881, miR-878, miR-743a, miR-743b, miR-465, miR-871, miR-880, are known to be expressed in mouse ESCs and were also expressed in rat PSCs; however, their function in pluripotency induction and regulation has not been directly shown 48– 50. [score:7]
A cluster of miRNAs, comprised of miR-463, miR-465, miR-471, miR-741, miR-743a, miR-743b, miR-871, miR-878, miR-880, miR-881, and miR-883, was located on the X chromosome and was expressed at a high level in rat PSCs according to the sequencing data. [score:3]
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[+] score: 1
There were seven miRNAs reduced by over 50% (miR-380-5p, miR-139-5p, miR-743b-5p, miR-212-3p, miR-132-5p, miR-3592, and miR-201-5p) after liraglutide treatment. [score:1]
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[+] score: 1
With these criteria we identified eight miRNAs: miR-140-3p, miR-140-5p,,, miR-208b-3p,, miR-743b-5p, and miR-879-3p (Table  1). [score:1]
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