miRNA Search Results

sort by 8 publications mentioning mmu-mir-465c-1 Open access articles that are associated with the species Mus musculus and mention the gene name mir-465c-1. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.
1	[+] score: 26 Other miRNAs from this paper: mmu-mir-201, mmu-mir-465a, mmu-mir-547, mmu-mir-465b-1, mmu-mir-465b-2, mmu-mir-465c-2, mmu-mir-465d B) Pri-miRNA FISH images of pachytene cells expressing miR-465 in Spo11 null and Brca1 [Δ11/Δ11] mutants (defective in XY silencing). [score:3] S5 FigCombined DNA / pri-miRNA FISH for miR-465 shows expression of miR-465 from the autosomal, transgenic locus (arrows) but not from the X locus (arrowhead). [score:3] We targeted the X-miRNA miR-465, present in six copies in cluster 4 (Fig 1D). [score:3] MiR-465 expression pattern recapitulates that of cluster 4 miRNAs (Fig 1D). [score:3] This proved to be the case: in the few Spo11 null and Brca1 pachytene cells in which the miR-465 locus, identified using DNA FISH, lay within a γH2AFX domain (Spo11 null: n = 2 out of 54 cells; Brca1 [Δ11/Δ11]: n = 2 out of 15 cells), no pri-miR-465 expression could be observed (Fig 2C). [score:3] S4 FigPri-miRNA FISH shows that miR-465 is silent in wild type pachytene cells. [score:1] Detection of pri-miR-465 by pri-miRNA FISH in miRBAC line 1 transgenic pachytene spermatocytes. [score:1] Top: Four variants of the miR-465 gene are repeated in the genome at the XA7 locus (see Fig 1D). [score:1] Pri-miRNA FISH shows that miR-465 is silent in wild type pachytene cells. [score:1] For miR-465-specific pri-miRNA FISH, a mix of nine amino-allyl -modified oligonucleotides labeled with fluorolink Cy3 were used as probes (S1 Table). [score:1] Pri-miR-465-specific oligonucleotide probes and BAC probes were used for RNA and DNA FISH respectively. [score:1] We observed the same results using our miR-465-specific pri-miRNA FISH protocol on X-miRBAC line 1 (S5 Fig) (100%, n = 9). [score:1] We subsequently repeated the analysis of cluster 4 X-miRNAs using our oligonucleotide RNA FISH approach that specifically detects pri-miRNAs for the six copies of miR-465. [score:1] Global DNA alignment of the precursors of the miR-465 variants is shown. [score:1] C) In some rare pachytene cell, the miR-465 locus is found underneath the silencing body that forms in Spo11 null and Brca1 [Δ11/Δ11] spermatocytes. [score:1] In addition, we performed miR-465-specific pri-miRNA FISH in a second MSCI mutant, the Brca1 [Δ11/Δ11] mo del [17, 18]. [score:1] [1 to 20 of 16 sentences]
2	[+] score: 16 Other miRNAs from this paper: mmu-mir-152, mmu-mir-465a, mmu-mir-743a, mdo-mir-152, mmu-mir-743b, mmu-mir-880, mmu-mir-883b, mmu-mir-465b-1, mmu-mir-465b-2, mmu-mir-465c-2, mmu-mir-465d The miRNA expression profiling of sterile (PWD×B6)F1 and fertile (B6×PWD)F1 14.5dpp testes showed 1.5- to 2-fold upregulation of Mir883b-3p, Mir465a/b/c-3p and Mir465a/b-5p in sterile males, while Mir743a, Mir743-5p, Mir880 and Mir465c-5p showed 1.2- to 4-fold down-regulation (Figure 3C, D). [score:9] The critical region also contains the Mir465 cluster of miRNA genes, which show a significant difference in expression between reciprocal F1 hybrids. [score:3] Significant overexpression of Mir465 cluster in PWD germ cells is shown in red. [score:2] Only the Mir465 [PWD] cluster displayed a significant increase of expression in the first meiotic prophase of PWD and B6 sorted testicular cells (Figure 3A, B). [score:2] [1 to 20 of 4 sentences]
3	[+] score: 15 Other miRNAs from this paper: mmu-mir-128-1, mmu-mir-298, mmu-mir-342, mmu-mir-200c, mmu-mir-128-2, mmu-mir-665, mmu-mir-683-1, mmu-mir-465c-2, mmu-mir-466d, mmu-mir-683-2 Similarly, 342 genes potentially downregulated (targets of mmu-miR-128 and mmu-miR-342-5p) and 200 potentially upregulated genes (targets of mmu-miR-465c-5p, mmu-miR-466d-3p, mmu-miR-466d-5p, mmu-miR-665, mmu-miR-683) in the colon were identified (Table S4). [score:11] qRT-PCR was performed using SYBR Green qPCR Master Mix (Fermentas) on a Mastercycler Realplex [4] (Eppendorf) using the following primers:For mature miRNA expression: the universal primer provided in the NCode [TM] miRNA first-strand cDNA synthesis kit was used together with one of the following forward primer: mmu-miR-665: 5′-ACCAGG AGG CTG AGG TCC CT-3′mmu-miR-128: 5′-TCACAGTGAACCGGTCTCTTT-3′ mmu-mir-200c: 5′-CGTCTTACCCAGCAGTGTTTGG-3′ mmu-miR-342-5p: 5′-AGGGGTGCTATCTGTGATTGAG-3′ mmu-miR-466d-3p: 5′-TATACATACACGCACACATAG-3′ mmu-miR-466d-5p: 5′-TGTGTGTGCGTACATGTACATG-3′ mmu-miR-465c-5p: 5′-TATTTAGAATGGCGCTGATCTG-3′ mmu-miR-683: 5′-CCTGCTGTAAGCTGTGTCCTC-3′ mmu-miR-665: 5′-ACCAGGAGGCTGAGGTCCCT-3′ mmu-miR-298: 5′-GGCAGAGGAGGGCTGTTCTTCCC-3′ For Abcc3 expression:Forward 5′-CTT CTT TTC CCG CTT GTC TTT-3′;Reverse 5′- CCT CCT CAG ACA GAG ACC AGA-3′. [score:2] qRT-PCR was performed using SYBR Green qPCR Master Mix (Fermentas) on a Mastercycler Realplex [4] (Eppendorf) using the following primers: For mature miRNA expression: the universal primer provided in the NCode [TM] miRNA first-strand cDNA synthesis kit was used together with one of the following forward primer: mmu-miR-665: 5′-ACCAGG AGG CTG AGG TCC CT-3′ mmu-miR-128: 5′-TCACAGTGAACCGGTCTCTTT-3′ mmu-mir-200c: 5′-CGTCTTACCCAGCAGTGTTTGG-3′ mmu-miR-342-5p: 5′-AGGGGTGCTATCTGTGATTGAG-3′ mmu-miR-466d-3p: 5′-TATACATACACGCACACATAG-3′ mmu-miR-466d-5p: 5′-TGTGTGTGCGTACATGTACATG-3′ mmu-miR-465c-5p: 5′-TATTTAGAATGGCGCTGATCTG-3′ mmu-miR-683: 5′-CCTGCTGTAAGCTGTGTCCTC-3′ mmu-miR-665: 5′-ACCAGGAGGCTGAGGTCCCT-3′ mmu-miR-298: 5′-GGCAGAGGAGGGCTGTTCTTCCC-3′ For Abcc3 expression: Forward 5′-CTT CTT TTC CCG CTT GTC TTT-3′; Reverse 5′- CCT CCT CAG ACA GAG ACC AGA-3′. [score:2] [1 to 20 of 3 sentences]
4	[+] score: 14 Other miRNAs from this paper: hsa-mir-26a-1, hsa-mir-26b, mmu-mir-141, mmu-mir-199a-1, hsa-mir-199a-1, mmu-mir-200b, mmu-mir-205, hsa-mir-199a-2, hsa-mir-199b, hsa-mir-205, hsa-mir-200b, mmu-mir-290a, mmu-mir-291a, mmu-mir-292a, mmu-mir-293, mmu-mir-294, mmu-mir-295, mmu-mir-302a, hsa-mir-141, mmu-mir-200a, mmu-mir-26a-1, mmu-mir-26b, hsa-mir-200c, mmu-mir-200c, mmu-mir-26a-2, mmu-mir-199a-2, mmu-mir-199b, hsa-mir-200a, hsa-mir-302a, hsa-mir-26a-2, hsa-mir-302b, hsa-mir-302c, hsa-mir-302d, hsa-mir-367, hsa-mir-372, rno-mir-26a, rno-mir-26b, rno-mir-141, rno-mir-199a, rno-mir-200c, rno-mir-200a, rno-mir-200b, rno-mir-205, rno-mir-290, rno-mir-291a, rno-mir-292, hsa-mir-429, mmu-mir-429, rno-mir-429, mmu-mir-463, mmu-mir-465a, mmu-mir-471, mmu-mir-367, mmu-mir-291b, mmu-mir-302b, mmu-mir-302c, mmu-mir-302d, mmu-mir-741, mmu-mir-743a, mmu-mir-743b, mmu-mir-871, mmu-mir-880, mmu-mir-881, mmu-mir-883a, mmu-mir-883b, mmu-mir-465b-1, mmu-mir-465b-2, mmu-mir-465c-2, mmu-mir-878, rno-mir-743b, rno-mir-871, rno-mir-878, rno-mir-880, rno-mir-881, rno-mir-883, rno-mir-463, rno-mir-471, rno-mir-743a, hsa-mir-302e, hsa-mir-302f, rno-mir-293, rno-mir-294, rno-mir-295-1, rno-mir-465, rno-mir-3551, rno-mir-291b, rno-mir-3580, rno-mir-741, rno-mir-295-2, rno-mir-6325, mmu-mir-292b, mmu-mir-465d, mmu-mir-290b Several miRNAs, such as members of the miR-183-96-182 cluster, miR-741, miR-881, miR-878, miR-743a, miR-743b, miR-465, miR-871, miR-880, are known to be expressed in mouse ESCs and were also expressed in rat PSCs; however, their function in pluripotency induction and regulation has not been directly shown 48– 50. [score:7] In addition, we found that the rno-miR-novel-8 miRNA was located less than 10 kb from miR-871, mir-3580 and miR-465, which were upregulated in rat PSCs. [score:4] A cluster of miRNAs, comprised of miR-463, miR-465, miR-471, miR-741, miR-743a, miR-743b, miR-871, miR-878, miR-880, miR-881, and miR-883, was located on the X chromosome and was expressed at a high level in rat PSCs according to the sequencing data. [score:3] [1 to 20 of 3 sentences]
5	[+] score: 12 Other miRNAs from this paper: mmu-let-7g, mmu-let-7i, mmu-mir-132, mmu-mir-145a, mmu-mir-146a, mmu-mir-181a-2, mmu-mir-205, mmu-mir-143, mmu-mir-296, mmu-let-7d, mmu-mir-130b, mmu-let-7a-1, mmu-let-7a-2, mmu-let-7b, mmu-let-7c-1, mmu-let-7c-2, mmu-let-7e, mmu-let-7f-1, mmu-let-7f-2, mmu-mir-20a, mmu-mir-21a, mmu-mir-26a-1, mmu-mir-26b, mmu-mir-29c, mmu-mir-92a-2, mmu-mir-93, mmu-mir-34a, mmu-mir-17, mmu-mir-25, mmu-mir-212, mmu-mir-181a-1, mmu-mir-26a-2, mmu-mir-92a-1, mmu-mir-181b-1, mmu-mir-181c, mmu-mir-181b-2, mmu-mir-434, mmu-mir-465a, mmu-mir-592, mmu-mir-743a, mmu-mir-181d, mmu-mir-743b, mmu-mir-465b-1, mmu-mir-465b-2, mmu-mir-465c-2, mmu-mir-145b, mmu-mir-21b, mmu-let-7j, mmu-mir-21c, mmu-let-7k, mmu-mir-465d Several members of the miR-465 and miR-743 families were up-regulated in both young and aged df/df mice, although they were expressed at lower levels than the previously discussed miRNAs. [score:6] miR-465 was previously detected as one of the most highly expressed miRNAs in the newborn mouse ovary, despite being undetectable in the adult ovary [6]. [score:3] The mir-465 cluster is located in the X chromosome, and is strongly expressed in the testis, although not detected in other tissues [6]. [score:3] [1 to 20 of 3 sentences]
6	[+] score: 7 Other miRNAs from this paper: mmu-mir-207, mmu-mir-290a, mmu-mir-292a, mmu-mir-298, mmu-mir-15a, mmu-mir-16-1, mmu-mir-465a, mmu-mir-465b-1, mmu-mir-465b-2, mmu-mir-465c-2, mmu-mir-292b, mmu-mir-465d, mmu-mir-290b For instance, mmu-miR-290 was up-regulated in all organs except forestomach; mmu-miR-465 was down-regulated in lung, spleen and glandular stomach. [score:7] [1 to 20 of 1 sentences]
7	[+] score: 2 Other miRNAs from this paper: mmu-let-7g, mmu-let-7i, mmu-mir-126a, mmu-mir-130a, mmu-mir-132, mmu-mir-30e, mmu-mir-291a, mmu-let-7d, mmu-mir-130b, mmu-let-7a-1, mmu-let-7a-2, mmu-let-7b, mmu-let-7c-1, mmu-let-7c-2, mmu-let-7e, mmu-let-7f-1, mmu-let-7f-2, mmu-mir-26b, mmu-mir-17, mmu-mir-212, mmu-mir-92a-1, mmu-mir-128-2, mmu-mir-215, mmu-mir-449a, mmu-mir-485, mmu-mir-1843a, mmu-mir-3058, mmu-mir-449c, mmu-mir-146b, mmu-mir-467b, mmu-mir-709, mmu-mir-711, mmu-mir-490, mmu-mir-465c-2, mmu-mir-467d, mmu-mir-449b, mmu-mir-877, mmu-mir-466l, mmu-mir-669i, mmu-mir-669h, mmu-mir-467h, mmu-mir-1251, mmu-mir-3067, mmu-mir-3074-1, mmu-mir-344f, mmu-mir-3962, mmu-mir-1843b, mmu-mir-3473d, mmu-let-7j, mmu-let-7k, mmu-mir-126b Eleven miRNAs were randomly selected for qPCR analysis for each age: GD 17.0 miR-1843-5p, miR-485-3p, miR-711, miR-3962, miR-3067-3p, miR-212-3p, miR-669i, miR-877, miR-26b-3p, miR-465c-3p, let-7b-3p; GD 18.0 miR-1843-5p, miR-485-3p, miR-3473d, miR-132-5p, miR-3074-1-3p, miR-128-2-5p, miR-130b-5p, miR-490-5p, miR-669h-3p, miR-3058-5p, miR-146b. [score:1] A statistically significant effect of flutamide was observed for seven of these miRNAs (miR-26b-3p, let-7b-3p, miR-465c-3p, miR-669h-3p, miR-3058-5p, miR-146b, miR-1843-5p), and a trend toward a statistically significant effect was observed for another miRNA (miR-130b-5p) (Fig. 2b, c). [score:1] [1 to 20 of 2 sentences]
8	[+] score: 1 Other miRNAs from this paper: mmu-mir-30a, mmu-mir-30b, mmu-mir-141, mmu-mir-151, mmu-mir-10b, mmu-mir-191, mmu-mir-143, mmu-mir-30e, mmu-mir-34c, mmu-mir-34b, mmu-mir-30c-1, mmu-mir-30c-2, mmu-mir-30d, mmu-mir-21a, mmu-mir-10a, mmu-mir-139, mmu-mir-375, mmu-mir-196b, mmu-mir-465a, mmu-mir-466a, mmu-mir-467a-1, mmu-mir-669a-1, mmu-mir-669b, mmu-mir-669a-2, mmu-mir-669a-3, mmu-mir-467b, mmu-mir-669c, mmu-mir-465b-1, mmu-mir-465b-2, mmu-mir-465c-2, mmu-mir-466b-1, mmu-mir-466b-2, mmu-mir-466b-3, mmu-mir-466c-1, mmu-mir-466e, mmu-mir-466f-1, mmu-mir-466f-2, mmu-mir-466f-3, mmu-mir-466g, mmu-mir-466h, mmu-mir-467c, mmu-mir-467d, mmu-mir-466d, mmu-mir-208b, mmu-mir-467e, mmu-mir-466l, mmu-mir-669k, mmu-mir-669g, mmu-mir-669d, mmu-mir-466i, mmu-mir-669j, mmu-mir-669f, mmu-mir-669i, mmu-mir-669h, mmu-mir-466f-4, mmu-mir-466k, mmu-mir-467f, mmu-mir-466j, mmu-mir-669e, mmu-mir-467g, mmu-mir-467h, mmu-mir-669l, mmu-mir-669m-1, mmu-mir-669m-2, mmu-mir-669o, mmu-mir-669n, mmu-mir-466m, mmu-mir-669d-2, mmu-mir-466o, mmu-mir-467a-2, mmu-mir-669a-4, mmu-mir-669a-5, mmu-mir-467a-3, mmu-mir-466c-2, mmu-mir-669a-6, mmu-mir-467a-4, mmu-mir-466b-4, mmu-mir-669a-7, mmu-mir-467a-5, mmu-mir-466b-5, mmu-mir-669p-1, mmu-mir-467a-6, mmu-mir-669a-8, mmu-mir-466b-6, mmu-mir-669a-9, mmu-mir-467a-7, mmu-mir-466b-7, mmu-mir-669p-2, mmu-mir-467a-8, mmu-mir-669a-10, mmu-mir-467a-9, mmu-mir-669a-11, mmu-mir-467a-10, mmu-mir-669a-12, mmu-mir-466p, mmu-mir-466n, mmu-mir-466b-8, mmu-mir-466q, mmu-mir-6240, mmu-mir-30f, mmu-mir-465d, mmu-mir-466c-3 Prominent among these were members of the let7, miR-30, miR-465, miR-466, miR-467, and miR-669 clusters. [score:1] [1 to 20 of 1 sentences]

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8 publications mentioning mmu-mir-465c-1

Open access articles that are associated with the species Mus musculus and mention the gene name mir-465c-1. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

[+] score: 26

Other miRNAs from this paper: mmu-mir-201, mmu-mir-465a, mmu-mir-547, mmu-mir-465b-1, mmu-mir-465b-2, mmu-mir-465c-2, mmu-mir-465d

B) Pri-miRNA FISH images of pachytene cells expressing miR-465 in Spo11 null and Brca1 [Δ11/Δ11] mutants (defective in XY silencing). [score:3]

S5 FigCombined DNA / pri-miRNA FISH for miR-465 shows expression of miR-465 from the autosomal, transgenic locus (arrows) but not from the X locus (arrowhead). [score:3]

We targeted the X-miRNA miR-465, present in six copies in cluster 4 (Fig 1D). [score:3]

MiR-465 expression pattern recapitulates that of cluster 4 miRNAs (Fig 1D). [score:3]

This proved to be the case: in the few Spo11 null and Brca1 pachytene cells in which the miR-465 locus, identified using DNA FISH, lay within a γH2AFX domain (Spo11 null: n = 2 out of 54 cells; Brca1 [Δ11/Δ11]: n = 2 out of 15 cells), no pri-miR-465 expression could be observed (Fig 2C). [score:3]

S4 FigPri-miRNA FISH shows that miR-465 is silent in wild type pachytene cells. [score:1]

Detection of pri-miR-465 by pri-miRNA FISH in miRBAC line 1 transgenic pachytene spermatocytes. [score:1]

Top: Four variants of the miR-465 gene are repeated in the genome at the XA7 locus (see Fig 1D). [score:1]

Pri-miRNA FISH shows that miR-465 is silent in wild type pachytene cells. [score:1]

For miR-465-specific pri-miRNA FISH, a mix of nine amino-allyl -modified oligonucleotides labeled with fluorolink Cy3 were used as probes (S1 Table). [score:1]

Pri-miR-465-specific oligonucleotide probes and BAC probes were used for RNA and DNA FISH respectively. [score:1]

We observed the same results using our miR-465-specific pri-miRNA FISH protocol on X-miRBAC line 1 (S5 Fig) (100%, n = 9). [score:1]

We subsequently repeated the analysis of cluster 4 X-miRNAs using our oligonucleotide RNA FISH approach that specifically detects pri-miRNAs for the six copies of miR-465. [score:1]

Global DNA alignment of the precursors of the miR-465 variants is shown. [score:1]

C) In some rare pachytene cell, the miR-465 locus is found underneath the silencing body that forms in Spo11 null and Brca1 [Δ11/Δ11] spermatocytes. [score:1]

In addition, we performed miR-465-specific pri-miRNA FISH in a second MSCI mutant, the Brca1 [Δ11/Δ11] mo del [17, 18]. [score:1]

[1 to 20 of 16 sentences]

[+] score: 16

Other miRNAs from this paper: mmu-mir-152, mmu-mir-465a, mmu-mir-743a, mdo-mir-152, mmu-mir-743b, mmu-mir-880, mmu-mir-883b, mmu-mir-465b-1, mmu-mir-465b-2, mmu-mir-465c-2, mmu-mir-465d

The miRNA expression profiling of sterile (PWD×B6)F1 and fertile (B6×PWD)F1 14.5dpp testes showed 1.5- to 2-fold upregulation of Mir883b-3p, Mir465a/b/c-3p and Mir465a/b-5p in sterile males, while Mir743a, Mir743-5p, Mir880 and Mir465c-5p showed 1.2- to 4-fold down-regulation (Figure 3C, D). [score:9]

The critical region also contains the Mir465 cluster of miRNA genes, which show a significant difference in expression between reciprocal F1 hybrids. [score:3]

Significant overexpression of Mir465 cluster in PWD germ cells is shown in red. [score:2]

Only the Mir465 [PWD] cluster displayed a significant increase of expression in the first meiotic prophase of PWD and B6 sorted testicular cells (Figure 3A, B). [score:2]

[1 to 20 of 4 sentences]

[+] score: 15

Other miRNAs from this paper: mmu-mir-128-1, mmu-mir-298, mmu-mir-342, mmu-mir-200c, mmu-mir-128-2, mmu-mir-665, mmu-mir-683-1, mmu-mir-465c-2, mmu-mir-466d, mmu-mir-683-2

Similarly, 342 genes potentially downregulated (targets of mmu-miR-128 and mmu-miR-342-5p) and 200 potentially upregulated genes (targets of mmu-miR-465c-5p, mmu-miR-466d-3p, mmu-miR-466d-5p, mmu-miR-665, mmu-miR-683) in the colon were identified (Table S4). [score:11]

qRT-PCR was performed using SYBR Green qPCR Master Mix (Fermentas) on a Mastercycler Realplex [4] (Eppendorf) using the following primers:For mature miRNA expression: the universal primer provided in the NCode [TM] miRNA first-strand cDNA synthesis kit was used together with one of the following forward primer: mmu-miR-665: 5′-ACCAGG AGG CTG AGG TCC CT-3′mmu-miR-128: 5′-TCACAGTGAACCGGTCTCTTT-3′ mmu-mir-200c*: 5′-CGTCTTACCCAGCAGTGTTTGG-3′ mmu-miR-342-5p: 5′-AGGGGTGCTATCTGTGATTGAG-3′ mmu-miR-466d-3p: 5′-TATACATACACGCACACATAG-3′ mmu-miR-466d-5p: 5′-TGTGTGTGCGTACATGTACATG-3′ mmu-miR-465c-5p: 5′-TATTTAGAATGGCGCTGATCTG-3′ mmu-miR-683: 5′-CCTGCTGTAAGCTGTGTCCTC-3′ mmu-miR-665: 5′-ACCAGGAGGCTGAGGTCCCT-3′ mmu-miR-298: 5′-GGCAGAGGAGGGCTGTTCTTCCC-3′ For Abcc3 expression:Forward 5′-CTT CTT TTC CCG CTT GTC TTT-3′;Reverse 5′- CCT CCT CAG ACA GAG ACC AGA-3′. [score:2]

qRT-PCR was performed using SYBR Green qPCR Master Mix (Fermentas) on a Mastercycler Realplex [4] (Eppendorf) using the following primers: For mature miRNA expression: the universal primer provided in the NCode [TM] miRNA first-strand cDNA synthesis kit was used together with one of the following forward primer: mmu-miR-665: 5′-ACCAGG AGG CTG AGG TCC CT-3′ mmu-miR-128: 5′-TCACAGTGAACCGGTCTCTTT-3′ mmu-mir-200c*: 5′-CGTCTTACCCAGCAGTGTTTGG-3′ mmu-miR-342-5p: 5′-AGGGGTGCTATCTGTGATTGAG-3′ mmu-miR-466d-3p: 5′-TATACATACACGCACACATAG-3′ mmu-miR-466d-5p: 5′-TGTGTGTGCGTACATGTACATG-3′ mmu-miR-465c-5p: 5′-TATTTAGAATGGCGCTGATCTG-3′ mmu-miR-683: 5′-CCTGCTGTAAGCTGTGTCCTC-3′ mmu-miR-665: 5′-ACCAGGAGGCTGAGGTCCCT-3′ mmu-miR-298: 5′-GGCAGAGGAGGGCTGTTCTTCCC-3′ For Abcc3 expression: Forward 5′-CTT CTT TTC CCG CTT GTC TTT-3′; Reverse 5′- CCT CCT CAG ACA GAG ACC AGA-3′. [score:2]

[1 to 20 of 3 sentences]

[+] score: 14

Other miRNAs from this paper: hsa-mir-26a-1, hsa-mir-26b, mmu-mir-141, mmu-mir-199a-1, hsa-mir-199a-1, mmu-mir-200b, mmu-mir-205, hsa-mir-199a-2, hsa-mir-199b, hsa-mir-205, hsa-mir-200b, mmu-mir-290a, mmu-mir-291a, mmu-mir-292a, mmu-mir-293, mmu-mir-294, mmu-mir-295, mmu-mir-302a, hsa-mir-141, mmu-mir-200a, mmu-mir-26a-1, mmu-mir-26b, hsa-mir-200c, mmu-mir-200c, mmu-mir-26a-2, mmu-mir-199a-2, mmu-mir-199b, hsa-mir-200a, hsa-mir-302a, hsa-mir-26a-2, hsa-mir-302b, hsa-mir-302c, hsa-mir-302d, hsa-mir-367, hsa-mir-372, rno-mir-26a, rno-mir-26b, rno-mir-141, rno-mir-199a, rno-mir-200c, rno-mir-200a, rno-mir-200b, rno-mir-205, rno-mir-290, rno-mir-291a, rno-mir-292, hsa-mir-429, mmu-mir-429, rno-mir-429, mmu-mir-463, mmu-mir-465a, mmu-mir-471, mmu-mir-367, mmu-mir-291b, mmu-mir-302b, mmu-mir-302c, mmu-mir-302d, mmu-mir-741, mmu-mir-743a, mmu-mir-743b, mmu-mir-871, mmu-mir-880, mmu-mir-881, mmu-mir-883a, mmu-mir-883b, mmu-mir-465b-1, mmu-mir-465b-2, mmu-mir-465c-2, mmu-mir-878, rno-mir-743b, rno-mir-871, rno-mir-878, rno-mir-880, rno-mir-881, rno-mir-883, rno-mir-463, rno-mir-471, rno-mir-743a, hsa-mir-302e, hsa-mir-302f, rno-mir-293, rno-mir-294, rno-mir-295-1, rno-mir-465, rno-mir-3551, rno-mir-291b, rno-mir-3580, rno-mir-741, rno-mir-295-2, rno-mir-6325, mmu-mir-292b, mmu-mir-465d, mmu-mir-290b

Several miRNAs, such as members of the miR-183-96-182 cluster, miR-741, miR-881, miR-878, miR-743a, miR-743b, miR-465, miR-871, miR-880, are known to be expressed in mouse ESCs and were also expressed in rat PSCs; however, their function in pluripotency induction and regulation has not been directly shown 48– 50. [score:7]

In addition, we found that the rno-miR-novel-8 miRNA was located less than 10 kb from miR-871, mir-3580 and miR-465, which were upregulated in rat PSCs. [score:4]

A cluster of miRNAs, comprised of miR-463, miR-465, miR-471, miR-741, miR-743a, miR-743b, miR-871, miR-878, miR-880, miR-881, and miR-883, was located on the X chromosome and was expressed at a high level in rat PSCs according to the sequencing data. [score:3]

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[+] score: 12

Several members of the miR-465 and miR-743 families were up-regulated in both young and aged df/df mice, although they were expressed at lower levels than the previously discussed miRNAs. [score:6]

miR-465 was previously detected as one of the most highly expressed miRNAs in the newborn mouse ovary, despite being undetectable in the adult ovary [6]. [score:3]

The mir-465 cluster is located in the X chromosome, and is strongly expressed in the testis, although not detected in other tissues [6]. [score:3]

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[+] score: 7

Other miRNAs from this paper: mmu-mir-207, mmu-mir-290a, mmu-mir-292a, mmu-mir-298, mmu-mir-15a, mmu-mir-16-1, mmu-mir-465a, mmu-mir-465b-1, mmu-mir-465b-2, mmu-mir-465c-2, mmu-mir-292b, mmu-mir-465d, mmu-mir-290b

For instance, mmu-miR-290 was up-regulated in all organs except forestomach; mmu-miR-465 was down-regulated in lung, spleen and glandular stomach. [score:7]

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[+] score: 2

Eleven miRNAs were randomly selected for qPCR analysis for each age: GD 17.0 miR-1843-5p, miR-485-3p, miR-711, miR-3962, miR-3067-3p, miR-212-3p, miR-669i, miR-877, miR-26b-3p, miR-465c-3p, let-7b-3p; GD 18.0 miR-1843-5p, miR-485-3p, miR-3473d, miR-132-5p, miR-3074-1-3p, miR-128-2-5p, miR-130b-5p, miR-490-5p, miR-669h-3p, miR-3058-5p, miR-146b. [score:1]

A statistically significant effect of flutamide was observed for seven of these miRNAs (miR-26b-3p, let-7b-3p, miR-465c-3p, miR-669h-3p, miR-3058-5p, miR-146b, miR-1843-5p), and a trend toward a statistically significant effect was observed for another miRNA (miR-130b-5p) (Fig. 2b, c). [score:1]

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[+] score: 1

Other miRNAs from this paper: mmu-mir-30a, mmu-mir-30b, mmu-mir-141, mmu-mir-151, mmu-mir-10b, mmu-mir-191, mmu-mir-143, mmu-mir-30e, mmu-mir-34c, mmu-mir-34b, mmu-mir-30c-1, mmu-mir-30c-2, mmu-mir-30d, mmu-mir-21a, mmu-mir-10a, mmu-mir-139, mmu-mir-375, mmu-mir-196b, mmu-mir-465a, mmu-mir-466a, mmu-mir-467a-1, mmu-mir-669a-1, mmu-mir-669b, mmu-mir-669a-2, mmu-mir-669a-3, mmu-mir-467b, mmu-mir-669c, mmu-mir-465b-1, mmu-mir-465b-2, mmu-mir-465c-2, mmu-mir-466b-1, mmu-mir-466b-2, mmu-mir-466b-3, mmu-mir-466c-1, mmu-mir-466e, mmu-mir-466f-1, mmu-mir-466f-2, mmu-mir-466f-3, mmu-mir-466g, mmu-mir-466h, mmu-mir-467c, mmu-mir-467d, mmu-mir-466d, mmu-mir-208b, mmu-mir-467e, mmu-mir-466l, mmu-mir-669k, mmu-mir-669g, mmu-mir-669d, mmu-mir-466i, mmu-mir-669j, mmu-mir-669f, mmu-mir-669i, mmu-mir-669h, mmu-mir-466f-4, mmu-mir-466k, mmu-mir-467f, mmu-mir-466j, mmu-mir-669e, mmu-mir-467g, mmu-mir-467h, mmu-mir-669l, mmu-mir-669m-1, mmu-mir-669m-2, mmu-mir-669o, mmu-mir-669n, mmu-mir-466m, mmu-mir-669d-2, mmu-mir-466o, mmu-mir-467a-2, mmu-mir-669a-4, mmu-mir-669a-5, mmu-mir-467a-3, mmu-mir-466c-2, mmu-mir-669a-6, mmu-mir-467a-4, mmu-mir-466b-4, mmu-mir-669a-7, mmu-mir-467a-5, mmu-mir-466b-5, mmu-mir-669p-1, mmu-mir-467a-6, mmu-mir-669a-8, mmu-mir-466b-6, mmu-mir-669a-9, mmu-mir-467a-7, mmu-mir-466b-7, mmu-mir-669p-2, mmu-mir-467a-8, mmu-mir-669a-10, mmu-mir-467a-9, mmu-mir-669a-11, mmu-mir-467a-10, mmu-mir-669a-12, mmu-mir-466p, mmu-mir-466n, mmu-mir-466b-8, mmu-mir-466q, mmu-mir-6240, mmu-mir-30f, mmu-mir-465d, mmu-mir-466c-3

Prominent among these were members of the let7, miR-30, miR-465, miR-466, miR-467, and miR-669 clusters. [score:1]

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miRBase

8 publications mentioning mmu-mir-465c-1