| 1 |
[+]
score:
12
Other miRNAs from this paper: mmu-let-7g, mmu-let-7i, mmu-mir-132, mmu-mir-145a, mmu-mir-146a, mmu-mir-181a-2, mmu-mir-205, mmu-mir-143, mmu-mir-296, mmu-let-7d, mmu-mir-130b, mmu-let-7a-1, mmu-let-7a-2, mmu-let-7b, mmu-let-7c-1, mmu-let-7c-2, mmu-let-7e, mmu-let-7f-1, mmu-let-7f-2, mmu-mir-20a, mmu-mir-21a, mmu-mir-26a-1, mmu-mir-26b, mmu-mir-29c, mmu-mir-92a-2, mmu-mir-93, mmu-mir-34a, mmu-mir-17, mmu-mir-25, mmu-mir-212, mmu-mir-181a-1, mmu-mir-26a-2, mmu-mir-92a-1, mmu-mir-181b-1, mmu-mir-181c, mmu-mir-181b-2, mmu-mir-434, mmu-mir-465a, mmu-mir-592, mmu-mir-743a, mmu-mir-181d, mmu-mir-465b-1, mmu-mir-465b-2, mmu-mir-465c-1, mmu-mir-465c-2, mmu-mir-145b, mmu-mir-21b, mmu-let-7j, mmu-mir-21c, mmu-let-7k, mmu-mir-465d
Several members of the miR-465 and miR-743 families were up-regulated in both young and aged df/df mice, although they were expressed at lower levels than the previously discussed miRNAs.
[score:6]
While little is known about miR-743, one study demonstrated that miR-743 is down-regulated by increased oxidative stress, which in turn increases translation of genes involved in cellular protection mechanisms [67].
[score:6]
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| 2 |
[+]
score:
10
Other miRNAs from this paper: hsa-mir-26a-1, hsa-mir-26b, mmu-mir-141, mmu-mir-199a-1, hsa-mir-199a-1, mmu-mir-200b, mmu-mir-205, hsa-mir-199a-2, hsa-mir-199b, hsa-mir-205, hsa-mir-200b, mmu-mir-290a, mmu-mir-291a, mmu-mir-292a, mmu-mir-293, mmu-mir-294, mmu-mir-295, mmu-mir-302a, hsa-mir-141, mmu-mir-200a, mmu-mir-26a-1, mmu-mir-26b, hsa-mir-200c, mmu-mir-200c, mmu-mir-26a-2, mmu-mir-199a-2, mmu-mir-199b, hsa-mir-200a, hsa-mir-302a, hsa-mir-26a-2, hsa-mir-302b, hsa-mir-302c, hsa-mir-302d, hsa-mir-367, hsa-mir-372, rno-mir-26a, rno-mir-26b, rno-mir-141, rno-mir-199a, rno-mir-200c, rno-mir-200a, rno-mir-200b, rno-mir-205, rno-mir-290, rno-mir-291a, rno-mir-292, hsa-mir-429, mmu-mir-429, rno-mir-429, mmu-mir-463, mmu-mir-465a, mmu-mir-471, mmu-mir-367, mmu-mir-291b, mmu-mir-302b, mmu-mir-302c, mmu-mir-302d, mmu-mir-741, mmu-mir-743a, mmu-mir-871, mmu-mir-880, mmu-mir-881, mmu-mir-883a, mmu-mir-883b, mmu-mir-465b-1, mmu-mir-465b-2, mmu-mir-465c-1, mmu-mir-465c-2, mmu-mir-878, rno-mir-743b, rno-mir-871, rno-mir-878, rno-mir-880, rno-mir-881, rno-mir-883, rno-mir-463, rno-mir-471, rno-mir-743a, hsa-mir-302e, hsa-mir-302f, rno-mir-293, rno-mir-294, rno-mir-295-1, rno-mir-465, rno-mir-3551, rno-mir-291b, rno-mir-3580, rno-mir-741, rno-mir-295-2, rno-mir-6325, mmu-mir-292b, mmu-mir-465d, mmu-mir-290b
Several miRNAs, such as members of the miR-183-96-182 cluster, miR-741, miR-881, miR-878, miR-743a, miR-743b, miR-465, miR-871, miR-880, are known to be expressed in mouse ESCs and were also expressed in rat PSCs; however, their function in pluripotency induction and regulation has not been directly shown 48– 50.
[score:7]
A cluster of miRNAs, comprised of miR-463, miR-465, miR-471, miR-741, miR-743a, miR-743b, miR-871, miR-878, miR-880, miR-881, and miR-883, was located on the X chromosome and was expressed at a high level in rat PSCs according to the sequencing data.
[score:3]
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| 3 |
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score:
9
Other miRNAs from this paper: mmu-mir-152, mmu-mir-465a, mmu-mir-743a, mdo-mir-152, mmu-mir-880, mmu-mir-883b, mmu-mir-465b-1, mmu-mir-465b-2, mmu-mir-465c-1, mmu-mir-465c-2, mmu-mir-465d
The miRNA expression profiling of sterile (PWD×B6)F1 and fertile (B6×PWD)F1 14.5dpp testes showed 1.5- to 2-fold upregulation of Mir883b-3p, Mir465a/b/c-3p and Mir465a/b-5p in sterile males, while Mir743a, Mir743-5p, Mir880 and Mir465c-5p showed 1.2- to 4-fold down-regulation (Figure 3C, D).
[score:9]
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| 4 |
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score:
4
Other miRNAs from this paper: mmu-mir-30a, mmu-mir-99b, mmu-mir-146a, mmu-mir-24-1, mmu-mir-122, mmu-mir-106b, mmu-let-7c-1, mmu-let-7c-2, mmu-mir-24-2, mmu-mir-103-1, mmu-mir-103-2, mmu-mir-351, mmu-mir-542, mmu-mir-503, mmu-mir-709, mmu-mir-883a, mmu-mir-1195
Interestingly we also identified two upregulated miRNAs, mmu-miR-883a-3p and mmu-miR-743b-5p, that were localized on a second X-chromosomal cluster.
[score:4]
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| 5 |
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score:
3
To test this possibility, we first examined the levels of miRNAs known to be expressed in spermatocytes (miR-34C, miR-743, and miR-878) and spermatogonia (miR-718) [33, 40] by Taqman analysis.
[score:3]
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| 6 |
[+]
score:
1
Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-let-7b, hsa-let-7c, hsa-let-7d, hsa-let-7e, hsa-let-7f-1, hsa-let-7f-2, hsa-mir-17, hsa-mir-30a, hsa-mir-100, mmu-let-7g, mmu-let-7i, mmu-mir-30a, mmu-mir-30b, mmu-mir-182, mmu-mir-187, hsa-mir-30c-2, hsa-mir-30d, mmu-mir-30e, hsa-mir-182, hsa-mir-187, mmu-mir-290a, mmu-mir-294, mmu-mir-299a, mmu-mir-302a, mmu-let-7d, hsa-let-7g, hsa-let-7i, hsa-mir-30b, mmu-mir-30c-1, mmu-mir-30c-2, mmu-mir-30d, mmu-mir-200a, mmu-let-7a-1, mmu-let-7a-2, mmu-let-7b, mmu-let-7c-1, mmu-let-7c-2, mmu-let-7e, mmu-let-7f-1, mmu-let-7f-2, mmu-mir-17, mmu-mir-100, hsa-mir-30c-1, hsa-mir-200a, hsa-mir-302a, hsa-mir-299, hsa-mir-30e, hsa-mir-302b, hsa-mir-302c, hsa-mir-302d, hsa-mir-367, hsa-mir-371a, hsa-mir-372, hsa-mir-373, mmu-mir-133b, hsa-mir-133b, hsa-mir-512-1, hsa-mir-512-2, hsa-mir-520e, hsa-mir-515-1, hsa-mir-519e, hsa-mir-515-2, hsa-mir-519c, hsa-mir-520a, hsa-mir-519b, hsa-mir-520b, hsa-mir-517a, hsa-mir-519d, hsa-mir-521-2, hsa-mir-521-1, mmu-mir-367, hsa-mir-628, mmu-mir-302b, mmu-mir-302c, mmu-mir-302d, mmu-mir-743a, hsa-mir-888, hsa-mir-302e, hsa-mir-302f, hsa-mir-371b, mmu-mir-299b, mmu-let-7j, mmu-mir-30f, mmu-let-7k, mmu-mir-290b
In contrast, miR-743-5p showed no difference, probably because this miRNA had an extremely low value in TTF.
[score:1]
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| 7 |
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score:
1
Other miRNAs from this paper: mmu-mir-1a-1, mmu-mir-30a, mmu-mir-30b, mmu-mir-101a, mmu-mir-133a-1, mmu-mir-140, mmu-mir-145a, mmu-mir-151, mmu-mir-181a-2, mmu-mir-184, mmu-mir-195a, mmu-mir-30e, mmu-mir-301a, mmu-let-7d, mmu-mir-30c-1, mmu-mir-30c-2, mmu-mir-30d, mmu-mir-208a, mmu-mir-15a, mmu-mir-21a, mmu-mir-22, mmu-mir-322, mmu-mir-148b, mmu-mir-1a-2, mmu-mir-100, mmu-mir-210, mmu-mir-181a-1, mmu-mir-222, mmu-mir-133a-2, mmu-mir-370, mmu-mir-448, mmu-mir-451a, mmu-mir-463, mmu-mir-546, mmu-mir-541, mmu-mir-449c, mmu-mir-499, mmu-mir-711, mmu-mir-721, mmu-mir-881, mmu-mir-883a, mmu-mir-883b, mmu-mir-147, mmu-mir-873a, mmu-mir-208b, mmu-mir-1b, mmu-mir-1195, mmu-mir-1927, mmu-mir-1933, mmu-mir-1943, mmu-mir-669o, mmu-mir-3067, mmu-mir-3074-1, mmu-mir-3102, mmu-mir-3074-2, mmu-mir-3470a, mmu-mir-3470b, mmu-mir-5123, mmu-mir-195b, mmu-mir-145b, mmu-mir-21b, mmu-mir-21c, mmu-mir-873b, mmu-mir-451b, mmu-mir-30f
86 miR-873-as 1,016 e-miR-743b-5p 23.75 miR-449c-as 515e-miR-715 || 69.35 miR-541-as 439 e-miR-881* 56.21 miR-148b-as 336 e-miR-370 97.41 miR-546-as 333 e-miR-3067 100 miR-3074-as 262 e-miR-448-5p 100miR-451-as ‡ 286 e-miR-669o-5p 99.35 † Novel miR* that are processed within the expected window of the mature strand are labelled “generic”.
[score:1]
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