Stem-loop sequence hsa-mir-377

Accession

MI0000785

Symbol

HGNC:MIR377

Description

Homo sapiens miR-377 stem-loop

Gene family

MIPF0000018; mir-154

Stem-loop

uu              c   -    a    - uuu 
  gagcagagguugcc uug guga uucg c   a
  |||||||||||||| ||| |||| |||| |   u
  uuuguuuucaacgg aac cacu aagu g   u
-g              a   a    -    u uau 

Deep sequencing

49 reads, 5 experiments

Genome context

• Coordinates (GRCh37.p5): chr14: 101528387-101528455 [+]
• Overlapping transcripts:

  sense

  ENST00000362145 ; MIR377-201; exon 1

Clustered miRNAs

< 10kb from hsa-mir-377

• hsa-mir-487a: chr14: 101518783-101518862 [+]
• hsa-mir-382: chr14: 101520643-101520718 [+]
• hsa-mir-134: chr14: 101521024-101521096 [+]
• hsa-mir-668: chr14: 101521595-101521660 [+]
• hsa-mir-485: chr14: 101521756-101521828 [+]
• hsa-mir-323b: chr14: 101522556-101522637 [+]
• hsa-mir-154: chr14: 101526092-101526175 [+]
• hsa-mir-496: chr14: 101526910-101527011 [+]
• hsa-mir-377: chr14: 101528387-101528455 [+]
• hsa-mir-541: chr14: 101530832-101530915 [+]
• hsa-mir-409: chr14: 101531637-101531715 [+]
• hsa-mir-412: chr14: 101531784-101531874 [+]
• hsa-mir-369: chr14: 101531935-101532004 [+]
• hsa-mir-410: chr14: 101532249-101532328 [+]
• hsa-mir-656: chr14: 101533061-101533138 [+]

Database links

• EMBL: AY882333;AY882333
• ENTREZGENE: 494326;MIR377
• HGNC: 31870;MIR377

Mature sequence hsa-miR-377-5p

• Accession: MIMAT0004689
• Previous IDs: hsa-miR-377*
• Sequence: 7 - agagguugcccuuggugaauuc - 28
• Deep sequencing: 31 reads, 1 experiments
• Evidence: experimental; cloned [3]
• Predicted targets:
  • DIANA-MICROT:hsa-miR-377-5p
  • MICRORNA.ORG:hsa-miR-377-5p
  • MIRDB:hsa-miR-377-5p
  • RNA22-HSA:hsa-miR-377-5p
  • TARGETMINER:hsa-miR-377-5p
  • PICTAR-VERT:hsa-miR-377

Mature sequence hsa-miR-377-3p

• Accession: MIMAT0000730
• Previous IDs: hsa-miR-377
• Sequence: 45 - aucacacaaaggcaacuuuugu - 66
• Deep sequencing: 18 reads, 5 experiments
• Evidence: experimental; cloned [1-3]
• Validated targets:
  • TARBASE:hsa-miR-377-3p
• Predicted targets:
  • DIANA-MICROT:hsa-miR-377-3p
  • MICRORNA.ORG:hsa-miR-377-3p
  • MIRDB:hsa-miR-377-3p
  • RNA22-HSA:hsa-miR-377-3p
  • TARGETMINER:hsa-miR-377-3p
  • TARGETSCAN-VERT:hsa-miR-377
  • PICTAR-VERT:hsa-miR-377

References

1. PMID:15891114 "Clustering and conservation patterns of human microRNAs" Altuvia Y, Landgraf P, Lithwick G, Elefant N, Pfeffer S, Aravin A, Brownstein MJ, Tuschl T, Margalit H Nucleic Acids Res. 33:2697-2706(2005).
2. PMID:16274478 "Identification of clustered microRNAs using an ab initio prediction method" Sewer A, Paul N, Landgraf P, Aravin A, Pfeffer S, Brownstein MJ, Tuschl T, van Nimwegen E, Zavolan M BMC Bioinformatics. 6:267(2005).
3. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).