Stem-loop sequence hsa-mir-519b

Accession MI0003151
Symbol HGNC:MIR519B
Description Homo sapiens miR-519b stem-loop
Gene family MIPF0000020; mir-515
Stem-loop 
  u  u    c            a         guug  u 
ca gc guga ccucuagaggga gcgcuuucu    uc g
|| || |||| |||||||||||| |||||||||    || a
gu ug cauu ggagauuuuccu cgugaaaga    ag a
  u  u    u            a         --aa  a
Get sequence
Deep sequencing
21 reads, 3 experiments
Comments

The 5' arm of this precursor expresses a product related to miR-526 (previously named miR-526c here). Landgraf et al. confirm mature miRNA expression from both arms of the precursor [2], leading to the -5p, -3p designations. The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2]. The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context
Coordinates (GRCh37.p5) Overlapping transcripts
chr19: 54198467-54198547 [+]
intergenic
Clustered miRNAs
< 10kb from hsa-mir-519b
hsa-mir-519c chr19: 54189723-54189809 [+]
hsa-mir-1283-1 chr19: 54191735-54191821 [+]
hsa-mir-520a chr19: 54194135-54194219 [+]
hsa-mir-526b chr19: 54197647-54197729 [+]
hsa-mir-519b chr19: 54198467-54198547 [+]
hsa-mir-525 chr19: 54200787-54200871 [+]
hsa-mir-523 chr19: 54201639-54201725 [+]
hsa-mir-518f chr19: 54203269-54203355 [+]
hsa-mir-520b chr19: 54204481-54204541 [+]
hsa-mir-518b chr19: 54205991-54206073 [+]
Database links

Mature sequence hsa-miR-519b-5p

Accession MIMAT0005454
Sequence

13 -  

cucuagagggaagcgcuuucug

 - 34

Get sequence
Deep sequencing 8 reads, 2 experiments
Evidence experimental; array-cloned [1], cloned [2]
Predicted targets

Mature sequence hsa-miR-519b-3p

Accession MIMAT0002837
Previous IDs hsa-miR-519b
Sequence

51 -  

aaagugcauccuuuuagagguu

 - 72

Get sequence
Deep sequencing 13 reads, 3 experiments
Evidence experimental; array-cloned [1], cloned [2]
Validated targets
Predicted targets

References

1
PMID:15965474 "Identification of hundreds of conserved and nonconserved human microRNAs" Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z Nat Genet. 37:766-770(2005).
2
PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).