Stem-loop sequence hsa-mir-520a

Accession

MI0003149

Symbol

HGNC:MIR520A

Description

Homo sapiens miR-520a stem-loop

Gene family

MIPF0000020; mir-515

Stem-loop

         u   cc                    g  g    
cucaggcug gac  uccagagggaaguacuuucu uu ucu 
||||||||| |||  |||||||||||||||||||| || || g
gaguuuggc uug  agguuucccuucgugaaaga aa aga 
         u   uc                    a  g    

Deep sequencing

16 reads, 4 experiments

Genome context

• Coordinates (GRCh37.p5): chr19: 54194135-54194219 [+]
• Overlapping transcripts:

  intergenic

Clustered miRNAs

< 10kb from hsa-mir-520a

• hsa-mir-520f: chr19: 54185413-54185499 [+]
• hsa-mir-515-2: chr19: 54188263-54188345 [+]
• hsa-mir-519c: chr19: 54189723-54189809 [+]
• hsa-mir-1283-1: chr19: 54191735-54191821 [+]
• hsa-mir-520a: chr19: 54194135-54194219 [+]
• hsa-mir-526b: chr19: 54197647-54197729 [+]
• hsa-mir-519b: chr19: 54198467-54198547 [+]
• hsa-mir-525: chr19: 54200787-54200871 [+]
• hsa-mir-523: chr19: 54201639-54201725 [+]
• hsa-mir-518f: chr19: 54203269-54203355 [+]

Database links

• EMBL: AY785926;AY785926
• EMBL: AY882292;AY882292
• ENTREZGENE: 574467;MIR520A
• HGNC: 32099;MIR520A

Mature sequence hsa-miR-520a-5p

• Accession: MIMAT0002833
• Previous IDs: hsa-miR-520a*
• Sequence: 15 - cuccagagggaaguacuuucu - 35
• Deep sequencing: 3 reads, 1 experiments
• Evidence: experimental; array-cloned [1], cloned [2]
• Predicted targets:
  • DIANA-MICROT:hsa-miR-520a-5p
  • MICRORNA.ORG:hsa-miR-520a-5p
  • MIRDB:hsa-miR-520a-5p
  • RNA22-HSA:hsa-miR-520a-5p
  • TARGETMINER:hsa-miR-520a-5p
  • TARGETSCAN-VERT:hsa-miR-520a-5p

Mature sequence hsa-miR-520a-3p

• Accession: MIMAT0002834
• Previous IDs: hsa-miR-520a
• Sequence: 53 - aaagugcuucccuuuggacugu - 74
• Deep sequencing: 11 reads, 3 experiments
• Evidence: experimental; array-cloned [1]
• Validated targets:
  • MIRTARBASE:hsa-miR-520a-3p
  • TARBASE:hsa-miR-520a-3p
• Predicted targets:
  • DIANA-MICROT:hsa-miR-520a-3p
  • MICRORNA.ORG:hsa-miR-520a-3p
  • MIRDB:hsa-miR-520a-3p
  • RNA22-HSA:hsa-miR-520a-3p
  • TARGETMINER:hsa-miR-520a-3p
  • TARGETSCAN-VERT:hsa-miR-520a-3p

References

1. PMID:15965474 "Identification of hundreds of conserved and nonconserved human microRNAs" Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z Nat Genet. 37:766-770(2005).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).