Stem-loop sequence hsa-mir-515-1

Accession

MI0003144

Symbol

HGNC:MIR515-1

Description

Homo sapiens miR-515-1 stem-loop

Gene family

MIPF0000020; mir-515

Stem-loop

     u     c  u           a    uu      gu 
ucuca gcagu au cuccaaaagaa gcac  ucuguu  c
||||| ||||| || ||||||||||| ||||  ||||||  u
agagu uguca ug gagguuuucuu cgug  agacga  g
     u     u  c           c    --      aa 

Deep sequencing

2 reads, 1 experiments

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context

• Coordinates (GRCh37.p5): chr19: 54182257-54182339 [+]
• Overlapping transcripts:

  intergenic

Clustered miRNAs

< 10kb from hsa-mir-515-1

• hsa-mir-512-2: chr19: 54172411-54172508 [+]
• hsa-mir-1323: chr19: 54175222-54175294 [+]
• hsa-mir-498: chr19: 54177451-54177574 [+]
• hsa-mir-520e: chr19: 54178965-54179051 [+]
• hsa-mir-515-1: chr19: 54182257-54182339 [+]
• hsa-mir-519e: chr19: 54183194-54183277 [+]
• hsa-mir-520f: chr19: 54185413-54185499 [+]
• hsa-mir-515-2: chr19: 54188263-54188345 [+]
• hsa-mir-519c: chr19: 54189723-54189809 [+]
• hsa-mir-1283-1: chr19: 54191735-54191821 [+]

Database links

• EMBL: AY785919;AY785919
• EMBL: AY785947;AY785947
• ENTREZGENE: 574462;MIR515-1
• HGNC: 32094;MIR515-1

Mature sequence hsa-miR-515-5p

• Accession: MIMAT0002826
• Sequence: 14 - uucuccaaaagaaagcacuuucug - 37
• Deep sequencing: 4 reads, 1 experiments
• Evidence: experimental; array-cloned [1], cloned [2]
• Predicted targets:
  • DIANA-MICROT:hsa-miR-515-5p
  • MICRORNA.ORG:hsa-miR-515-5p
  • MIRDB:hsa-miR-515-5p
  • RNA22-HSA:hsa-miR-515-5p
  • TARGETMINER:hsa-miR-515-5p
  • TARGETSCAN-VERT:hsa-miR-515-5p

Mature sequence hsa-miR-515-3p

• Accession: MIMAT0002827
• Sequence: 51 - gagugccuucuuuuggagcguu - 72
• Evidence: experimental; array-cloned [1], cloned [2]
• Validated targets:
  • MIRTARBASE:hsa-miR-515-3p
  • TARBASE:hsa-miR-515-3p
• Predicted targets:
  • DIANA-MICROT:hsa-miR-515-3p
  • MICRORNA.ORG:hsa-miR-515-3p
  • MIRDB:hsa-miR-515-3p
  • RNA22-HSA:hsa-miR-515-3p
  • TARGETMINER:hsa-miR-515-3p
  • TARGETSCAN-VERT:hsa-miR-515-3p

References

1. PMID:15965474 "Identification of hundreds of conserved and nonconserved human microRNAs" Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z Nat Genet. 37:766-770(2005).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).