Stem-loop sequence mmu-mir-378a

Accession

MI0000795

Previous IDs

mmu-mir-378

Symbol

MGI:Mir378

Description

Mus musculus miR-378 stem-loop

Gene family

MIPF0000168; mir-378

Stem-loop

   g  c              ugu      ccu 
agg cu cugacuccaggucc   guguua   c
||| || ||||||||||||||   ||||||    
ucc ga gacugagguucagg   cacgau   g
   g  a              --u      aaa 

Deep sequencing

3969842 reads, 97 experiments

Genome context

• Coordinates (GRCm38): chr18: 61397835-61397900 [-]
• Overlapping transcripts:

  sense

  OTTMUST00000059063 ; Ppargc1b-003; intron 1

  OTTMUST00000058872 ; Ppargc1b-002; intron 1

  OTTMUST00000058693 ; Ppargc1b-001; intron 1

  ENSMUST00000142134 ; Ppargc1b-003; intron 1

  ENSMUST00000063307 ; Ppargc1b-002; intron 1

  ENSMUST00000075299 ; Ppargc1b-001; intron 1

  antisense

  ENSMUST00000175285 ; AC116595.1-201; exon 1

Database links

• ENTREZGENE: 723889;Mir378
• MGI: 3617791;Mir378

Mature sequence mmu-miR-378a-5p

• Accession: MIMAT0000742
• Previous IDs: mmu-miR-378;mmu-miR-378*;mmu-miR-378-5p
• Sequence: 5 - cuccugacuccagguccugugu - 26
• Deep sequencing: 5885 reads, 76 experiments
• Evidence: experimental; cloned [1-2], Solexa [3-4]
• Predicted targets:
  • DIANA-MICROT:mmu-miR-378a-5p
  • MICRORNA.ORG:mmu-miR-378a-5p
  • MIRDB:mmu-miR-378a-5p
  • RNA22-MMU:mmu-miR-378a-5p

Mature sequence mmu-miR-378a-3p

• Accession: MIMAT0003151
• Previous IDs: mmu-miR-422b;mmu-miR-378;mmu-miR-378-3p
• Sequence: 43 - acuggacuuggagucagaagg - 63
• Deep sequencing: 3682251 reads, 82 experiments
• Evidence: experimental; cloned [2], Solexa [3-4]
• Validated targets:
  • TARBASE:mmu-miR-378a-3p
• Predicted targets:
  • DIANA-MICROT:mmu-miR-378a-3p
  • MICRORNA.ORG:mmu-miR-378a-3p
  • MIRDB:mmu-miR-378a-3p
  • RNA22-MMU:mmu-miR-378a-3p
  • TARGETSCAN-VERT:mmu-miR-378

References

1. PMID:15538371 "A pancreatic islet-specific microRNA regulates insulin secretion" Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M Nature. 432:226-230(2004).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
3. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
4. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).