Stem-loop sequence emu-mir-2b

Accession MI0017800
Description Echinococcus multilocularis miR-2b stem-loop
Gene family MIPF0000049; mir-2
Community annotation

This text is a summary paragraph taken from the Wikipedia entry entitled mir-2_microRNA_precursor. miRBase and Rfam are facilitating community annotation of microRNA families and entries in Wikipedia. Read more ...

The mir-2 microRNA family includes the microRNA genes mir-2 and mir-13 (MIPF0000049). Mir-2 is widespread in invertebrates, and it is the largest family of microRNAs in the model species Drosophila melanogaster. MicroRNAs from this family are produced from the 3' arm of the precursor hairpin. Leaman et al. showed that the miR-2 family regulates cell survival by translational repression of proapoptotic factors. Based on computational prediction of targets, a role in neural development and maintenance has been suggested.

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Stem-loop
   --       cg        ---     g    uc     a 
5'   ugucagu  guguccca   agggu guga  uacuc g
     |||||||  ||||||||   ||||| ||||  ||||| u
3'   acggucg  cacagggu   ucccg cacu  augag u
   cg       ua        ucg     a    --     g 
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Confidence
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Genome context
Coordinates (WTSI3) Overlapping transcripts
scaffold_007728: 10027294-10027369 [-]
intergenic
Clustered miRNAs
< 10kb from emu-mir-2b
emu-mir-71 scaffold_007728: 10027494-10027579 [-]
emu-mir-2c scaffold_007728: 10027399-10027476 [-]
emu-mir-2b scaffold_007728: 10027294-10027369 [-]

Mature sequence emu-miR-2b

Accession MIMAT0020256
Sequence

43 - 

uaucacagcccugcuugggaca

 - 64

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Evidence not experimental

References

1
PMID:21219906 "Identification of Echinococcus granulosus microRNAs and their expression in different life cycle stages and parasite genotypes" Cucher M, Prada L, Mourglia-Ettlin G, Dematteis S, Camicia F, Asurmendi S, Rosenzvit M Int J Parasitol. 41:439-448(2011).