Stem-loop sequence hsa-mir-4524a

Accession

MI0016891

Previous IDs

hsa-mir-4524

Description

Homo sapiens miR-4524a stem-loop

Gene family

MIPF0001330; mir-4524

Stem-loop

-   c             a         cugcag 
 gaa gauagcagcauga ccugucuca      a
 ||| ||||||||||||| |||||||||       
 cuu cuaucgucguauu ggacagagu      a
a   c             c         uuuauu 

Deep sequencing

3 reads, 2 experiments

Genome context

• Coordinates (GRCh37.p5): chr17: 67095705-67095773 [-]
• Overlapping transcripts:

  sense

  ENST00000284425 ; ABCA6-201; intron 22

  ENST00000284425 ; ABCA6-201; intron 22

  ENST00000284425 ; ABCA6-201; intron 22

  antisense

  ENST00000581569 ; MIR4524B-201; exon 1

Clustered miRNAs

< 10kb from hsa-mir-4524a

• hsa-mir-4524a: chr17: 67095705-67095773 [-]
• hsa-mir-4524b: chr17: 67095683-67095797 [+]

Database links

• ENTREZGENE: 100616316;MIR4524

Mature sequence hsa-miR-4524a-5p

• Accession: MIMAT0019062
• Previous IDs: hsa-miR-4524
• Sequence: 6 - auagcagcaugaaccugucuca - 27
• Evidence: experimental; Solexa [1-2,4]
• Predicted targets:
  • DIANA-MICROT:hsa-miR-4524a-5p
  • MIRDB:hsa-miR-4524a-5p
  • TARGETMINER:hsa-miR-4524a-5p

Mature sequence hsa-miR-4524a-3p

• Accession: MIMAT0019063
• Previous IDs: hsa-miR-4524*
• Sequence: 42 - ugagacaggcuuaugcugcuau - 63
• Deep sequencing: 3 reads, 2 experiments
• Evidence: experimental; Solexa [1-2,4]
• Predicted targets:
  • DIANA-MICROT:hsa-miR-4524a-3p
  • MIRDB:hsa-miR-4524a-3p
  • TARGETMINER:hsa-miR-4524a-3p

References

1. PMID:20733160 "Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs" Jima DD, Zhang J, Jacobs C, Richards KL, Dunphy CH, Choi WW, Au WY, Srivastava G, Czader MB, Rizzieri DA, Lagoo AS, Lugar PL, Mann KP, Flowers CR, Bernal-Mizrachi L, Naresh KN, Evens AM, Gordon LI, Luftig M, Friedman DR, Weinberg JB, Thompson MA, Gill JI, Blood. 116:e118-e127(2010).
2. PMID:21199797 "Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene" Persson H, Kvist A, Rego N, Staaf J, Vallon-Christersson J, Luts L, Loman N, Jonsson G, Naya H, Hoglund M, Borg A, Rovira C Cancer Res. 71:78-86(2011).
3. PMID:21911355 "miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades" Friedlander MR, Mackowiak SD, Li N, Chen W, Rajewsky N Nucleic Acids Res. 40:37-52(2012).
4. PMID:21807764 "Deep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome" Joyce CE, Zhou X, Xia J, Ryan C, Thrash B, Menter A, Zhang W, Bowcock AM Hum Mol Genet. 20:4025-4040(2011).