Stem-loop sequence rco-MIR156a

AccessionMI0013370
DescriptionRicinus communis miR156a stem-loop
Gene family MIPF0000008; MIR156
Community annotation

This text is a summary paragraph taken from the Wikipedia entry entitled mir-156_microRNA_precursor. miRBase and Rfam are facilitating community annotation of microRNA families and entries in Wikipedia. Read more ...

MicroRNA (miRNA) precursor mir-156 is a family of plant non-coding RNA. This microRNA has now been predicted or experimentally confirmed in a range of plant species (MIPF0000008). Animal miRNAs are transcribed as ~70 nucleotide precursors and subsequently processed by the Dicer enzyme to give a ~22 nucleotide product. In plants the precursor sequences may be longer, and the carpel factory (caf) enzyme appears to be involved in processing. In this case the mature sequence comes from the 5' arm of the precursor, and both Arabidopsis thaliana and rice genomes contain a number of related miRNA precursors which give rise to almost identical mature sequences. The extents of the hairpin precursors are not generally known and are estimated based on hairpin prediction. The products are thought to have regulatory roles through complementarity to mRNA.

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Stem-loop
   ----    gu      -    a           u    uucuu    aucg 
5'     gggc  gacaga agag gugagcacaca gguu     gcau    a
       ||||  |||||| |||| ||||||||||| ||||     ||||    u
3'     cccg  cugucu ucuc cacucgugugu ucga     cgua    a
   ucca    --      a    c           c    -uuuu    guuc 
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Confidence
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Genome context
Coordinates (TIGR0.1) Overlapping transcripts
29912: 261490-261586 [-]
intergenic

Mature sequence rco-miR156a

Accession MIMAT0014144
Sequence

6 - 

ugacagaagagagugagcaca

 - 26

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Evidence experimental; RT-PCR [1]

References

1
PMID:19942686 "Conservation and divergence of microRNAs and their functions in Euphorbiaceous plants" Zeng C, Wang W, Zheng Y, Chen X, Bo W, Song S, Zhang W, Peng M Nucleic Acids Res. 38:981-995(2010).