Stem-loop sequence hsv1-mir-H4

Accession MI0008939
Description Herpes Simplex Virus 1 miR-H4 stem-loop
Stem-loop 
       -    a     u             g   g   a 
gccgggg uggu gaguu gacaggcaagcau ugc ugc g
||||||| |||| ||||| ||||||||||||| ||| |||  
cggcucu aucg cucaa cuguccguucgug aug gcg a
       g    -     u             -   a   g
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Comments

The mature sequence from the 5' arm of this hairpin was named miR-LAT-ICP34.5 in [2].

Mature sequence hsv1-miR-H4-5p

Accession MIMAT0008401
Previous IDs hsv1-miR-H4-5p;hsv1-miR-H4
Sequence

9 -  

gguagaguuugacaggcaagca

 - 30

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Evidence experimental; 454 [1], qRT-PCR [1], Solexa [3-4]

Mature sequence hsv1-miR-H4-3p

Accession MIMAT0008402
Previous IDs hsv1-miR-H4-3p;hsv1-miR-H4*
Sequence

54 -  

cuugccugucuaacucgcuagu

 - 75

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Evidence experimental; 454 [1], qRT-PCR [1], cloned [2], Solexa [3]

References

1
PMID:18596690 "MicroRNAs expressed by herpes simplex virus 1 during latent infection regulate viral mRNAs" Umbach JL, Kramer MF, Jurak I, Karnowski HW, Coen DM, Cullen BR Nature. 454:780-783(2008).
2
PMID:18678906 "An acutely and latently expressed herpes simplex virus 2 viral microRNA inhibits expression of ICP34.5, a viral neurovirulence factor" Tang S, Bertke AS, Patel A, Wang K, Cohen JI, Krause PR Proc Natl Acad Sci U S A. 105:10931-10936(2008).
3
PMID:19656888 "Analysis of human alphaherpesvirus microRNA expression in latently infected human trigeminal ganglia" Umbach JL, Nagel MA, Cohrs RJ, Gilden DH, Cullen BR J Virol. 83:10677-10683(2009).
4
PMID:20181707 "Numerous conserved and divergent microRNAs expressed by herpes simplex viruses 1 and 2" Jurak I, Kramer MF, Mellor JC, van Lint AL, Roth FP, Knipe DM, Coen DM J Virol. 84:4659-4672(2010).