Stem-loop sequence mml-mir-122a

AccessionMI0007613
DescriptionMacaca mulatta miR-122a stem-loop
Gene family MIPF0000095; mir-122
Community annotation

This text is a summary paragraph taken from the Wikipedia entry entitled MiR-122. miRBase and Rfam are facilitating community annotation of microRNA families and entries in Wikipedia. Read more ...

miR-122 is a miRNA that is conserved between vertebrate species. miR-122 is not present in invertebrates, and no close paralogs of miR-122 have been detected. miR-122 expression is specific to the liver, where it has been implicated as a regulator of fatty-acid metabolism in mouse studies. Reduced miR-122 levels are associated with hepatocellular carcinoma. miR-122 also plays an important positive role in the regulation of hepatitis C virus replication.

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Stem-loop
c     c  -      gg       c           --u  c 
 cuuag ag agcugu  aguguga aaugguguuug   gu u
 ||||| || ||||||  ||||||| |||||||||||   ||  
 ggauc uc ucgaua  ucacacu uuaccgcaaac   ca a
c     a  a      aa       a           uau  a 
Get sequence
Deep sequencing
8933 reads, 145 reads per million, 8 experiments
Confidence
Feedback: Do you believe this miRNA is real?
Genome context
Coordinates (CR_1.0) Overlapping transcripts
chr18: 52644492-52644576 [+]
intergenic
Database links

Mature sequence mml-miR-122a-5p

Accession MIMAT0006180
Sequence

15 - 

uggagugugacaaugguguuug

 - 36

Get sequence
Deep sequencing15 reads, 4 experiments
Evidence experimental; Illumina [2]
Predicted targets

Mature sequence mml-miR-122a-3p

Accession MIMAT0026813
Sequence

52 - 

acgccauuaucacacuaaaua

 - 72

Get sequence
Evidence experimental; Illumina [2]

References

1
2
PMID:23034410 "Birth and expression evolution of mammalian microRNA genes" Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H Genome Res. 23:34-45(2013).