Stem-loop sequence mml-mir-34c

AccessionMI0007605 (change log)
DescriptionMacaca mulatta miR-34c stem-loop
Gene family MIPF0000039; mir-34
Community annotation

This text is a summary paragraph taken from the Wikipedia entry entitled mir-34_microRNA_precursor_family. miRBase and Rfam are facilitating community annotation of microRNA families and entries in Wikipedia. Read more ...

The mir-34 microRNA precursor family are non-coding RNA molecules that, in mammals, give rise to three major mature miRNAs. The miR-34 family members were discovered computationally and later verified experimentally. The precursor miRNA stem-loop is processed in the cytoplasm of the cell, with the predominant miR-34 mature sequence excised from the 5' arm of the hairpin. The mature miR-34a is a part of the p53 tumor suppressor network; therefore, it is hypothesized that miR-34 dysregulation is involved in the development of some cancers.

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        ag     a   a    a     c      c  a 
5' agucu  uuacc ggc gugu guuag ugauug ug u
   |||||  ||||| ||| |||| ||||| |||||| ||  
3' uuaga  aaugg ccg caca caauc acuaac au a
        aa     a   g    c     -      c  g 
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Genome context
Coordinates (Mmul_8.0.1; GCA_000772875.3) Overlapping transcripts
chr14: 104382905-104382981 [+]
Clustered miRNAs
< 10kb from mml-mir-34c
mml-mir-34bchr14: 104382402-104382485 [+]
mml-mir-34cchr14: 104382905-104382981 [+]
Database links

Mature sequence mml-miR-34c-5p

Accession MIMAT0006175

13 - 


 - 35

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Evidence by similarity; MI0000743
Database links
Predicted targets

Mature sequence mml-miR-34c-3p

Accession MIMAT0006176

46 - 


 - 67

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Evidence by similarity; MI0000743
Predicted targets