Stem-loop sequence mml-mir-34b

DescriptionMacaca mulatta miR-34b stem-loop
Gene family MIPF0000039; mir-34
Community annotation

This text is a summary paragraph taken from the Wikipedia entry entitled mir-34_microRNA_precursor_family. miRBase and Rfam are facilitating community annotation of microRNA families and entries in Wikipedia. Read more ...

The mir-34 microRNA precursor family are non-coding RNA molecules that, in mammals, give rise to three major mature miRNAs. The miR-34 family members were discovered computationally and later verified experimentally. The precursor miRNA stem-loop is processed in the cytoplasm of the cell, with the predominant miR-34 mature sequence excised from the 5' arm of the hairpin. The mature miR-34a is a part of the p53 tumor suppressor network; therefore, it is hypothesized that miR-34 dysregulation is involved in the development of some cancers.

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        cg    -gua       uca    c        -  g 
5' gugcu  guuu    ggcagug   uuag ugauugua cu u
   |||||  ||||    |||||||   |||| |||||||| || g
3' cacgg  caaa    ccgucac   aauc acuaacau gg g
        aa    acua       cuc    -        u  u 
Get sequence
Deep sequencing
2547 reads, 771 reads per million, 7 experiments
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Database links

Mature sequence mml-miR-34b

Accession MIMAT0006174

50 - 


 - 71

Get sequence
Deep sequencing15 reads, 3 experiments
Evidence by similarity; MI0000742
Predicted targets