Stem-loop sequence mml-mir-10b

Accession MI0007588
Description Macaca mulatta miR-10b stem-loop
Gene family MIPF0000033; mir-10
Community annotation

This text is a summary paragraph taken from the Wikipedia entry entitled mir-10_microRNA_precursor_family. miRBase and Rfam are facilitating community annotation of microRNA families and entries in Wikipedia. Read more ...

The miR-10 microRNA precursor is a short non-coding RNA gene involved in gene regulation. It is part of an RNA gene family which contains miR-10, miR-51, miR-57, miR-99 and miR-100. miR-10, miR-99 and miR-100 have now been predicted or experimentally confirmed in a wide range of species. (MIPF0000033, MIPF0000025) mir-51 and mir-57 have currently only been identified in the nematode Caenorhabditis elegans (MIPF0000268, MIPF0000271). microRNAs are transcribed as ~70 nucleotide precursors and subsequently processed by the Dicer enzyme to give a ~22 nucleotide product. In this case the mature sequence comes from the 5' arm of the precursor. The mature products are thought to have regulatory roles through complementarity to mRNA.

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Stem-loop
cca      guaa     u        a    g     c          -ug   u 
   gagguu    cguug cuauauau cccu uagaa cgaauuugug   gua c
   ||||||    ||||| |||||||| |||| ||||| ||||||||||   |||  
   cuucaa    guagc gguauaua gggg aucuu gcuuagacac   uau c
--a      aaac     u        a    -     a          uga   a 
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Confidence
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Genome context
Coordinates (MMUL1.0) Overlapping transcripts
12: 39792044-39792153 [+]
intergenic
Clustered miRNAs
< 10kb from mml-mir-10b
mml-mir-7164 12: 39791649-39791698 [+]
mml-mir-10b 12: 39792044-39792153 [+]
Database links

Mature sequence mml-miR-10b-5p

Accession MIMAT0006162
Sequence

27 - 

uacccuguagaaccgaauuugug

 - 49

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Evidence experimental; Solexa [23034410]
Predicted targets

Mature sequence mml-miR-10b-3p

Accession MIMAT0026798
Sequence

68 - 

agauucgauucuaggggaaua

 - 88

Get sequence
Evidence experimental; Solexa [23034410]

References

1
2
PMID:23034410 "Birth and expression evolution of mammalian microRNA genes" Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H Genome Res. 23:34-45(2013).