Stem-loop sequence mml-mir-10a

Accession MI0007587
Description Macaca mulatta miR-10a stem-loop
Gene family MIPF0000033; mir-10
Community annotation

This text is a summary paragraph taken from the Wikipedia entry entitled mir-10_microRNA_precursor_family. miRBase and Rfam are facilitating community annotation of microRNA families and entries in Wikipedia. Read more ...

The miR-10 microRNA precursor is a short non-coding RNA gene involved in gene regulation. It is part of an RNA gene family which contains miR-10, miR-51, miR-57, miR-99 and miR-100. miR-10, miR-99 and miR-100 have now been predicted or experimentally confirmed in a wide range of species. (MIPF0000033, MIPF0000025) mir-51 and mir-57 have currently only been identified in the nematode Caenorhabditis elegans (MIPF0000268, MIPF0000271). microRNAs are transcribed as ~70 nucleotide precursors and subsequently processed by the Dicer enzyme to give a ~22 nucleotide product. In this case the mature sequence comes from the 5' arm of the precursor. The mature products are thought to have regulatory roles through complementarity to mRNA.

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Stem-loop
----gauc   --c    uu        a    g     c          uaaggaa 
        ugu   uguc  cuguauau cccu uagau cgaauuugug       u
        |||   ||||  |||||||| |||| ||||| ||||||||||        
        aca   acag  gauguaua gggg aucua gcuuaaacac       u
cucgccuc   aau    uu        a    -     u          ugguguu 
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Confidence
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Genome context
Coordinates (MMUL1.0) Overlapping transcripts
16: 32809599-32809707 [-]
sense
ENSMMUT00000029348 ; HOXB6-201; intron 4
Database links

Mature sequence mml-miR-10a-5p

Accession MIMAT0006161
Sequence

22 - 

uacccuguagauccgaauuugug

 - 44

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Evidence experimental; Solexa [23034410]
Predicted targets

Mature sequence mml-miR-10a-3p

Accession MIMAT0026797
Sequence

64 - 

aaauucguaucuaggggaaua

 - 84

Get sequence
Evidence experimental; Solexa [23034410]

References

1
2
PMID:23034410 "Birth and expression evolution of mammalian microRNA genes" Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H Genome Res. 23:34-45(2013).