Stem-loop sequence mml-mir-9-3

Accession MI0007586
Description Macaca mulatta miR-9-3 stem-loop
Gene family MIPF0000014; mir-9
Community annotation

This text is a summary paragraph taken from the Wikipedia entry entitled mir-9/mir-79_microRNA_precursor_family. miRBase and Rfam are facilitating community annotation of microRNA families and entries in Wikipedia. Read more ...

The miR-9 microRNA (homologous to miR-79), is a short non-coding RNA gene involved in gene regulation. The mature ~21nt miRNAs are processed from hairpin precursor sequences by the Dicer enzyme. The dominant mature miRNA sequence is processed from the 5' arm of the mir-9 precursor, and from the 3' arm of the mir-79 precursor. The mature products are thought to have regulatory roles through complementarity to mRNA. In vertebrates, miR-9 is highly expressed in the brain, and is suggested to regulate neuronal differentiation. A number of specific targets of miR-9 have been proposed, including the transcription factor REST and its partner CoREST.

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Stem-loop
   g    cc       -  c               guau     c a 
5'  gagg  cguuucu cu uuugguuaucuagcu    gagug c c
    ||||  ||||||| || |||||||||||||||    ||||| | a
3'  cucu  guaaaga ga aagccaauagaucga    cucgc g g
   a    ca       u  -               -acu     c a 
Get sequence
Deep sequencing
48952 reads, 635 reads per million, 8 experiments
Confidence
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Database links

Mature sequence mml-miR-9-5p

Accession MIMAT0006160
Sequence

16 - 

ucuuugguuaucuagcuguauga

 - 38

Get sequence
Deep sequencing 19255 reads, 8 experiments
Evidence experimental; Illumina [2]
Predicted targets

Mature sequence mml-miR-9-3-3p

Accession MIMAT0031078
Sequence

55 - 

cucaagcuagauaaccgaaagu

 - 76

Get sequence
Evidence experimental; Illumina [2]

References

1
2
PMID:23034410 "Birth and expression evolution of mammalian microRNA genes" Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H Genome Res. 23:34-45(2013).