Stem-loop sequence mml-mir-9-2

Accession MI0007585
Description Macaca mulatta miR-9-2 stem-loop
Gene family MIPF0000014; mir-9
Community annotation

This text is a summary paragraph taken from the Wikipedia entry entitled mir-9/mir-79_microRNA_precursor_family. miRBase and Rfam are facilitating community annotation of microRNA families and entries in Wikipedia. Read more ...

The miR-9 microRNA (homologous to miR-79), is a short non-coding RNA gene involved in gene regulation. The mature ~21nt miRNAs are processed from hairpin precursor sequences by the Dicer enzyme. The dominant mature miRNA sequence is processed from the 5' arm of the mir-9 precursor, and from the 3' arm of the mir-79 precursor. The mature products are thought to have regulatory roles through complementarity to mRNA. In vertebrates, miR-9 is highly expressed in the brain, and is suggested to regulate neuronal differentiation. A number of specific targets of miR-9 have been proposed, including the transcription factor REST and its partner CoREST.

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Stem-loop
g    c     g   uc               g      ug a 
 gaag gaguu uua  uuugguuaucuagcu uaugag  u u
 |||| ||||| |||  ||||||||||||||| ||||||  |  
 cuuc cucaa aau  aagccaauagaucga auacuu  g u
a    -     a   ga               a      cu g 
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Confidence
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Genome context
Coordinates (MMUL1.0) Overlapping transcripts
6: 84955411-84955497 [-]
intergenic
Database links

Mature sequence mml-miR-9-5p

Accession MIMAT0006160
Sequence

16 - 

ucuuugguuaucuagcuguauga

 - 38

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Evidence experimental; Solexa [23034410]
Predicted targets

Mature sequence mml-miR-9-3p

Accession MIMAT0026796
Sequence

53 - 

auaaagcuagauaaccgaaagua

 - 75

Get sequence
Evidence experimental; Solexa [23034410]

References

1
2
PMID:23034410 "Birth and expression evolution of mammalian microRNA genes" Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H Genome Res. 23:34-45(2013).