Stem-loop sequence rno-mir-488

Accession MI0006168
Description Rattus norvegicus miR-488 stem-loop
Gene family MIPF0000318; mir-488
Stem-loop 
--aa  c   cu  c   u      a  c        -  u 
    uc ucu  cc aga aauggc cu ucaaacaa gu u
    || |||  || ||| |||||| || |||||||| ||  
    ag aga  gg ucu uugucg ga aguuuguu ca c
ucuc  a   cu  u   -      -  a        a  u
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Comments

The predominant miRNA cloned by Landgraf et al. has a 3' additional U residue, which is incompatible with the genome sequence [1].

Genome context
Coordinates (RGSC3.4) Overlapping transcripts
13: 73795102-73795180 [+]
sense
ENSRNOT00000007660 ; F1M5B8_RAT; intron 7
ENSRNOT00000007660 ; F1M5B8_RAT; intron 7
ENSRNOT00000007660 ; F1M5B8_RAT; intron 7
Database links
  • ENTREZGENE: 100314120;Mir488

Mature sequence rno-miR-488-5p

Accession MIMAT0017320
Previous IDs rno-miR-488*
Sequence

11 -  

cccagauaauggcacucucaa

 - 31

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Evidence experimental; SOLiD [2]
Predicted targets

Mature sequence rno-miR-488-3p

Accession MIMAT0005341
Previous IDs rno-miR-488
Sequence

49 -  

uugaaaggcuguuucuugguc

 - 69

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Evidence experimental; cloned [1], SOLiD [2]
Predicted targets

References

1
PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
2
PMID:20403161 "Small RNA expression and strain specificity in the rat" Linsen SE, de Wit E, de Bruijn E, Cuppen E BMC Genomics. 11:249(2010).