Stem-loop sequence hsa-mir-216b

Accession MI0005569
Symbol HGNC:MIR216B
Description Homo sapiens miR-216b stem-loop
Gene family MIPF0000054; mir-216
Stem-loop 
--g       gaa         a  --caaa      g  ac 
   cagacug   aaucucugc gg      ugugau uc  u
   |||||||   ||||||||| ||      |||||| ||   
   gucugac   uuagagaug cc      acacua ag  g
aca       auc         c  auucac      a  ga
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Comments

This sequence was identified as a miRNA candidate by Berezikov et al. using RAKE and MPSS techniques [1]. Expression was later confirmed by cloning [2].

Genome context
Coordinates (GRCh37.p5) Overlapping transcripts
chr2: 56227849-56227930 [-]
sense
OTTHUMT00000324929 ; AC011306.2-001; intron 2
OTTHUMT00000324929 ; AC011306.2-001; intron 2
OTTHUMT00000324929 ; AC011306.2-001; intron 2
ENST00000446139 ; AC011306.2-001; intron 2
ENST00000446139 ; AC011306.2-001; intron 2
ENST00000446139 ; AC011306.2-001; intron 2
Database links

Mature sequence hsa-miR-216b

Accession MIMAT0004959
Sequence

11 -  

aaaucucugcaggcaaauguga

 - 32

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Evidence experimental; cloned [2]
Predicted targets

References

1
PMID:16954537 "Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis" Berezikov E, van Tetering G, Verheul M, van de Belt J, van Laake L, Vos J, Verloop R, van de Wetering M, Guryev V, Takada S, van Zonneveld AJ, Mano H, Plasterk R, Cuppen E Genome Res. 16:1289-1298(2006).
2
PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).