Stem-loop sequence mmu-mir-877

Accession

MI0005553 (change log)

Symbol

MGI:Mir877

Description

Mus musculus miR-877 stem-loop

Gene family

MIPF0000392; mir-877

Literature search

17 open access papers mention mmu-mir-877
(25 sentences)

Stem-loop

   -gua      au  c c          agguaggccuugcggg 
5'     gaggag  gg g aggggacaca                u
       ||||||  || | ||||||||||                 
3'     cuccuc  cc c ucuccugugu                c
   gacc      --  u u          acagguucccaggugu 

Deep sequencing

15920 reads, 16 reads per million, 106 experiments

Confidence

Annotation confidence: not enough data

Feedback: Do you believe this miRNA is real?

Comments

This sequence was identified as a miRNA candidate by Berezikov et al. using RAKE and MPSS techniques [1]. Expression was later confirmed by cloning [2].

Genome context

• Coordinates (GRCm38; GCA_000001635.2): chr17: 35960730-35960814 [-]
• Overlapping transcripts:

  sense

  OTTMUST00000096569 ; Abcf1-001; intron 12

  ENSMUST00000043757 ; Abcf1-001; intron 12

Database links

• EntrezGene:Mir877
• MGI:Mir877
• RNAcentral:URS00006751F8_10090
• miRBase Tracker:MI0005553

Mature sequence mmu-miR-877-5p

• Accession: MIMAT0004861
• Previous IDs: mmu-miR-877
• Sequence: 1 - guagaggagauggcgcaggg - 20
• Deep sequencing: 14640 reads, 100 experiments
• Evidence: experimental; cloned [1-2], Illumina [4-5]
• Database links:
  • RNAcentral:URS00005240FD_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-877-5p
  • miRDB:mmu-miR-877-5p
  • microrna.org:mmu-miR-877-5p

Mature sequence mmu-miR-877-3p

• Accession: MIMAT0004862
• Previous IDs: mmu-miR-877*
• Sequence: 63 - uguccucuucucccuccuccca - 84
• Deep sequencing: 1225 reads, 86 experiments
• Evidence: experimental; cloned [1-2], Illumina [4-5]
• Database links:
  • RNAcentral:URS0000584A54_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-877-3p
  • miRDB:mmu-miR-877-3p
  • microrna.org:mmu-miR-877-3p

References

1. PMID:16954537 "Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis" Berezikov E, van Tetering G, Verheul M, van de Belt J, van Laake L, Vos J, Verloop R, van de Wetering M, Guryev V, Takada S, van Zonneveld AJ, Mano H, Plasterk R, Cuppen E Genome Res. 16:1289-1298(2006).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
3. PMID:17964270 "Mammalian mirtron genes" Berezikov E, Chung WJ, Willis J, Cuppen E, Lai EC Mol Cell. 28:328-336(2007).
4. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
5. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).