Stem-loop sequence mmu-mir-493

Accession

MI0005514

Symbol

MGI:Mir493

Description

Mus musculus miR-493 stem-loop

Gene family

MIPF0000230; mir-493

Stem-loop

-c  -        u            -        cauuuuu 
  gc cagggccu guacaugguagg cuuucauu       u
  || |||||||| |||||||||||| ||||||||        
  cg gucccgga cgugugucaucc ggaagugg       g
ac  u        c            u        cuuacac 

Deep sequencing

3491 reads, 42 experiments

Genome context

• Coordinates (GRCm38): chr12: 109580233-109580315 [+]
• Overlapping transcripts:

  intergenic

Clustered miRNAs

< 10kb from mmu-mir-493

• mmu-mir-673: chr12: 109571990-109572080 [+]
• mmu-mir-493: chr12: 109580233-109580315 [+]
• mmu-mir-337: chr12: 109585789-109585885 [+]
• mmu-mir-3544: chr12: 109585813-109585873 [-]
• mmu-mir-540: chr12: 109586080-109586146 [+]
• mmu-mir-665: chr12: 109586314-109586407 [+]
• mmu-mir-3070a: chr12: 109587943-109588031 [+]
• mmu-mir-3070b: chr12: 109588592-109588680 [+]

Database links

• ENTREZGENE: 100124466;Mir493
• MGI: 3718542;Mir493

Mature sequence mmu-miR-493-5p

• Accession: MIMAT0017276
• Previous IDs: mmu-miR-493*
• Sequence: 11 - uuguacaugguaggcuuuc - 29
• Deep sequencing: 1293 reads, 37 experiments
• Evidence: experimental; 454 [3], Solexa [4]
• Predicted targets:
  • DIANA-MICROT:mmu-miR-493-5p
  • MIRDB:mmu-miR-493-5p
  • RNA22-MMU:mmu-miR-493-5p

Mature sequence mmu-miR-493-3p

• Accession: MIMAT0004888
• Previous IDs: mmu-miR-493
• Sequence: 51 - ugaagguccuacugugugccagg - 73
• Deep sequencing: 2195 reads, 35 experiments
• Evidence: experimental; Solexa [2,4]
• Predicted targets:
  • DIANA-MICROT:mmu-miR-493-3p
  • MICRORNA.ORG:mmu-miR-493-3p
  • MIRDB:mmu-miR-493-3p
  • RNA22-MMU:mmu-miR-493-3p
  • TARGETSCAN-VERT:mmu-miR-493

References

1. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
2. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
3. PMID:20668074 "Identification and analysis of expression of novel microRNAs of murine gammaherpesvirus 68" Zhu JY, Strehle M, Frohn A, Kremmer E, Hofig KP, Meister G, Adler H J Virol. 84:10266-10275(2010).
4. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).