Stem-loop sequence mmu-mir-181d

Accession

MI0005450 (change log)

Symbol

MGI:Mir181d

Description

Mus musculus miR-181d stem-loop

Gene family

MIPF0000007; mir-181

Literature search

123 open access papers mention mmu-mir-181d
(652 sentences)

Stem-loop

   acaauua         g ug          guga  ag 
5'        acauucauu u  ucgguggguu    gg  g
          ||||||||| |  ||||||||||    ||   
3'        uguaaguag g  ggccacccag    cc  c
   -ugucac         g --          ---a  ga 

Deep sequencing

1430801 reads, 2.41e+03 reads per million, 107 experiments

Confidence

Annotation confidence: high

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Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context

• Coordinates (GRCm38; GCA_000001635.2): chr8: 84178716-84178787 [-]
• Overlapping transcripts:

  intergenic

Clustered miRNAs

< 10kb from mmu-mir-181d

• mmu-mir-181c: chr8: 84178873-84178961 [-]
• mmu-mir-181d: chr8: 84178716-84178787 [-]

Database links

• EntrezGene:Mir181d
• MGI:Mir181d
• RNAcentral:URS000075C512_10090
• miRBase Tracker:MI0005450

Mature sequence mmu-miR-181d-5p

• Accession: MIMAT0004324
• Previous IDs: mmu-miR-181d
• Sequence: 7 - aacauucauuguugucggugggu - 29
• Deep sequencing: 1429865 reads, 107 experiments
• Evidence: experimental; cloned [1-2], Illumina [3-4]
• Database links:
  • RNAcentral:URS0000236310_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-181d-5p
  • miRDB:mmu-miR-181d-5p
  • microrna.org:mmu-miR-181d-5p

Mature sequence mmu-miR-181d-3p

• Accession: MIMAT0017264
• Previous IDs: mmu-miR-181d*
• Sequence: 48 - cccaccgggggaugaauguca - 68
• Deep sequencing: 918 reads, 69 experiments
• Evidence: experimental; Illumina [4]
• Database links:
  • RNAcentral:URS0000111AD5_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-181d-3p
  • miRDB:mmu-miR-181d-3p

References

1. PMID:16766679 "Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes" Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N, Imai H Genes Dev. 20:1732-1743(2006).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
3. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
4. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).