Stem-loop sequence hsa-mir-759

Accession MI0004065
Description Homo sapiens miR-759 stem-loop
Gene family MIPF0000706; mir-759
Stem-loop 
              cc     u   ag          a   u  cu 
uaauaaauuaaaug  uaaac ggc  agugcaaaca uuu ga  c
||||||||||||||  ||||| |||  |||||||||| ||| ||   
auuguuuaauuuac  auuug ucg  ucacguuugu aaa cu  a
              aa     -   -g          -   u  ag
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Comments

Berezikov et al. proposed this sequence as a miRNA candidate based on the RAKE method [1]. Artzi et al. later showed that it is a homolog of a validated miRNA in mouse [2].

Genome context
Coordinates (GRCh37.p5) Overlapping transcripts
chr13: 53384185-53384275 [+]
sense
ENST00000390224 ; MIR759-201; exon 1
ENST00000390224 ; MIR759-201; exon 1
ENST00000390224 ; MIR759-201; exon 1
Database links
  • ENTREZGENE: 100313778;MIR759

Mature sequence hsa-miR-759

Accession MIMAT0010497
Sequence

24 -  

gcagagugcaaacaauuuugac

 - 45

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Evidence experimental; RAKE [1]
Predicted targets

References

1
PMID:16954537 "Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis" Berezikov E, van Tetering G, Verheul M, van de Belt J, van Laake L, Vos J, Verloop R, van de Wetering M, Guryev V, Takada S, van Zonneveld AJ, Mano H, Plasterk R, Cuppen E Genome Res. 16:1289-1298(2006).
2
PMID:18215311 "miRNAminer: a tool for homologous microRNA gene search" Artzi S, Kiezun A, Shomron N BMC Bioinformatics. 9:39(2008).