Stem-loop sequence hsa-mir-1185-1

Accession MI0003844
Symbol HGNC:MIR1185-1
Description Homo sapiens miR-1185-1 stem-loop
Gene family MIPF0000018; mir-154
Stem-loop 
u       u    -     ga a              a  uga 
 uugguac ugaa gagag  u cccuuuguauguuc cu   u
 ||||||| |||| |||||  | |||||||||||||| ||    
 aacuaug guuu uucuc  a gggggacauauaag gg   u
a       c    a     ag -              c  uaa
Get sequence
Deep sequencing
1050 reads, 10 experiments
Comments

This sequence was proposed as a miRNA candidate by Berezikov et al by RAKE analysis [1], and validated by cloning independently by Subramanian et al [2].

Genome context
Coordinates (GRCh37.p5) Overlapping transcripts
chr14: 101509314-101509399 [+]
intergenic
Clustered miRNAs
< 10kb from hsa-mir-1185-1
hsa-mir-495 chr14: 101500092-101500173 [+]
hsa-mir-376c chr14: 101506027-101506092 [+]
hsa-mir-376a-2 chr14: 101506406-101506485 [+]
hsa-mir-654 chr14: 101506556-101506636 [+]
hsa-mir-376b chr14: 101506773-101506872 [+]
hsa-mir-376a-1 chr14: 101507119-101507186 [+]
hsa-mir-300 chr14: 101507700-101507782 [+]
hsa-mir-1185-1 chr14: 101509314-101509399 [+]
hsa-mir-1185-2 chr14: 101510535-101510620 [+]
hsa-mir-381 chr14: 101512257-101512331 [+]
hsa-mir-487b chr14: 101512792-101512875 [+]
hsa-mir-539 chr14: 101513658-101513735 [+]
hsa-mir-889 chr14: 101514238-101514316 [+]
hsa-mir-544a chr14: 101514995-101515085 [+]
hsa-mir-655 chr14: 101515887-101515983 [+]
hsa-mir-487a chr14: 101518783-101518862 [+]
Database links

Mature sequence hsa-miR-1185-5p

Accession MIMAT0005798
Previous IDs hsa-miR-1185
Sequence

15 -  

agaggauacccuuuguauguu

 - 35

Get sequence
Deep sequencing 129 reads, 8 experiments
Evidence experimental; cloned [2]
Predicted targets

Mature sequence hsa-miR-1185-1-3p

Accession MIMAT0022838
Sequence

53 -  

auauacagggggagacucuuau

 - 74

Get sequence
Deep sequencing 986 reads, 5 experiments
Evidence not experimental
Predicted targets

References

1
PMID:16954537 "Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis" Berezikov E, van Tetering G, Verheul M, van de Belt J, van Laake L, Vos J, Verloop R, van de Wetering M, Guryev V, Takada S, van Zonneveld AJ, Mano H, Plasterk R, Cuppen E Genome Res. 16:1289-1298(2006).
2
PMID:17922033 "MicroRNA expression signature of human sarcomas" Subramanian S, Lui WO, Lee CH, Espinosa I, Nielsen TO, Heinrich MC, Corless CL, Fire AZ, van de Rijn M Oncogene. 27:2015-2026(2008).