Stem-loop sequence hsa-mir-33b

AccessionMI0003646 (change log)
Symbol HGNC:MIR33B
DescriptionHomo sapiens miR-33b stem-loop
Gene family MIPF0000070; mir-33
Community annotation

This text is a summary paragraph taken from the Wikipedia entry entitled miR-33. miRBase and Rfam are facilitating community annotation of microRNA families and entries in Wikipedia. Read more ...

miR-33 is a family of microRNA precursors, which are processed by the Dicer enzyme to give mature microRNAs. miR-33 is found in several animal species, including humans. In some species there is a single member of this family which gives the mature product mir-33. In humans there are two members of this family called mir-33a and mir-33b, which are located in intronic regions within two protein-coding genes for Sterol regulatory element-binding proteins (SREBP-2 and SREBP-1) respectively.

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   -----  ---    -   c   c  -          uu         g   g 
5'      gc   gggc ggc ccg gg ugcauugcug  gcauugcac ugu u
        ||   |||| ||| ||| || ||||||||||  ||||||||| ||| g
3'      cg   cccg ccg ggc cc acgugacggc  cgugacgug gcg a
   cacca  guc    g   a   -  g          uc         g   g 
Get sequence
Deep sequencing
6554 reads, 47.9 reads per million, 71 experiments
Confidence Annotation confidence: high
Feedback: Do you believe this miRNA is real?

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context
Coordinates (GRCh38; GCA_000001405.15) Overlapping transcripts
chr17: 17813836-17813931 [-]
OTTHUMT00000131929 ; TOM1L2-002; intron 1
OTTHUMT00000131928 ; TOM1L2-001; intron 1
OTTHUMT00000443246 ; TOM1L2-010; intron 1
OTTHUMT00000131931 ; TOM1L2-004; intron 1
OTTHUMT00000443248 ; TOM1L2-007; intron 1
OTTHUMT00000443249 ; TOM1L2-009; intron 1
OTTHUMT00000443250 ; TOM1L2-008; intron 1
OTTHUMT00000443252 ; TOM1L2-011; intron 1
OTTHUMT00000443253 ; TOM1L2-012; intron 1
ENST00000581396 ; TOM1L2-002; intron 1
ENST00000379504 ; TOM1L2-001; intron 1
ENST00000318094 ; TOM1L2-010; intron 1
ENST00000395739 ; TOM1L2-004; intron 1
ENST00000535933 ; TOM1L2-007; intron 1
ENST00000540946 ; TOM1L2-009; intron 1
ENST00000542206 ; TOM1L2-008; intron 1
ENST00000537091 ; TOM1L2-011; intron 1
ENST00000579586 ; TOM1L2-012; intron 1
Clustered miRNAs
< 10kb from hsa-mir-33b
hsa-mir-33bchr17: 17813836-17813931 [-]
hsa-mir-6777chr17: 17813480-17813545 [-]
Database links

Mature sequence hsa-miR-33b-5p

Accession MIMAT0003301
Previous IDshsa-miR-33b

16 - 


 - 35

Get sequence
Deep sequencing5362 reads, 65 experiments
Evidence experimental; SAGE [1], cloned [2]
Database links
Predicted targets

Mature sequence hsa-miR-33b-3p

Accession MIMAT0004811
Previous IDshsa-miR-33b*

54 - 


 - 75

Get sequence
Deep sequencing1041 reads, 42 experiments
Evidence experimental; cloned [2]
Database links
Predicted targets


PMID:16505370 "The colorectal microRNAome" Cummins JM, He Y, Leary RJ, Pagliarini R, Diaz LA Jr, Sjoblom T, Barad O, Bentwich Z, Szafranska AE, Labourier E, Raymond CK, Roberts BS, Juhl H, Kinzler KW, Vogelstein B, Velculescu VE Proc Natl Acad Sci U S A. 103:3687-3692(2006).
PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).