Stem-loop sequence hsa-mir-501

Accession

MI0003185

Symbol

HGNC:MIR501

Description

Homo sapiens miR-501 stem-loop

Gene family

MIPF0000139; mir-500

Stem-loop

    u       -u       u u   u     agag   uuu 
gcuc uccucuc  aauccuu g ccc gggug    ugc   c
|||| |||||||  ||||||| | ||| |||||    |||   u
cgag gggagag  uuaggaa c ggg cccac    acg   g
    u       uc       - -   -     -gua   uaa 

Deep sequencing

4530 reads, 25 experiments

Genome context

• Coordinates (GRCh37.p5): chrX: 49774330-49774413 [+]
• Overlapping transcripts:

  sense

  OTTHUMT00000056542 ; CLCN5-001; intron 3

  OTTHUMT00000056543 ; CLCN5-002; intron 3

  OTTHUMT00000109349 ; CLCN5-005; intron 3

  OTTHUMT00000056542 ; CLCN5-001; intron 3

  OTTHUMT00000056543 ; CLCN5-002; intron 3

  OTTHUMT00000109349 ; CLCN5-005; intron 3

  OTTHUMT00000056542 ; CLCN5-001; intron 3

  OTTHUMT00000056543 ; CLCN5-002; intron 3

  OTTHUMT00000109349 ; CLCN5-005; intron 3

  ENST00000376088 ; CLCN5-001; intron 3

  ENST00000376091 ; CLCN5-002; intron 3

  ENST00000482218 ; CLCN5-005; intron 3

  ENST00000450422 ; CLCN5-201; intron 3

  ENST00000376088 ; CLCN5-001; intron 3

  ENST00000376091 ; CLCN5-002; intron 3

  ENST00000482218 ; CLCN5-005; intron 3

  ENST00000450422 ; CLCN5-201; intron 3

  ENST00000376088 ; CLCN5-001; intron 3

  ENST00000376091 ; CLCN5-002; intron 3

  ENST00000482218 ; CLCN5-005; intron 3

Clustered miRNAs

< 10kb from hsa-mir-501

• hsa-mir-532: chrX: 49767754-49767844 [+]
• hsa-mir-188: chrX: 49768109-49768194 [+]
• hsa-mir-500a: chrX: 49773039-49773122 [+]
• hsa-mir-362: chrX: 49773572-49773636 [+]
• hsa-mir-501: chrX: 49774330-49774413 [+]
• hsa-mir-500b: chrX: 49775280-49775358 [+]
• hsa-mir-660: chrX: 49777849-49777945 [+]
• hsa-mir-502: chrX: 49779206-49779291 [+]

Database links

• EMBL: AY882271;AY882271
• ENTREZGENE: 574503;MIR501
• HGNC: 32135;MIR501

Mature sequence hsa-miR-501-5p

• Accession: MIMAT0002872
• Previous IDs: hsa-miR-501
• Sequence: 14 - aauccuuugucccugggugaga - 35
• Deep sequencing: 102 reads, 13 experiments
• Evidence: experimental; array-cloned [1], cloned [2]
• Predicted targets:
  • DIANA-MICROT:hsa-miR-501-5p
  • MICRORNA.ORG:hsa-miR-501-5p
  • MIRDB:hsa-miR-501-5p
  • RNA22-HSA:hsa-miR-501-5p
  • TARGETMINER:hsa-miR-501-5p
  • TARGETSCAN-VERT:hsa-miR-501-5p

Mature sequence hsa-miR-501-3p

• Accession: MIMAT0004774
• Sequence: 51 - aaugcacccgggcaaggauucu - 72
• Deep sequencing: 4428 reads, 19 experiments
• Evidence: experimental; cloned [2]
• Predicted targets:
  • DIANA-MICROT:hsa-miR-501-3p
  • MICRORNA.ORG:hsa-miR-501-3p
  • MIRDB:hsa-miR-501-3p
  • RNA22-HSA:hsa-miR-501-3p
  • TARGETMINER:hsa-miR-501-3p
  • TARGETSCAN-VERT:hsa-miR-501-3p

References

1. PMID:15965474 "Identification of hundreds of conserved and nonconserved human microRNAs" Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z Nat Genet. 37:766-770(2005).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).