Stem-loop sequence hsa-mir-500a

Accession

MI0003184

Previous IDs

hsa-mir-500

Symbol

HGNC:MIR500

Description

Homo sapiens miR-500a stem-loop

Gene family

MIPF0000139; mir-500

Stem-loop

    c c     -u         uac ug    agag   ugu 
gcuc c cucuc  aauccuugc   c  ggug    ugc   c
|||| | |||||  |||||||||   |  ||||    |||   u
cgag g gagag  uuaggaacg   g  ccac    acg   g
    a c     uc         --- gu    -gua   uaa 

Deep sequencing

4772 reads, 32 experiments

Genome context

• Coordinates (GRCh37.p5): chrX: 49773039-49773122 [+]
• Overlapping transcripts:

  sense

  OTTHUMT00000056542 ; CLCN5-001; intron 3

  OTTHUMT00000056543 ; CLCN5-002; intron 3

  OTTHUMT00000109349 ; CLCN5-005; intron 3

  OTTHUMT00000056542 ; CLCN5-001; intron 3

  OTTHUMT00000056543 ; CLCN5-002; intron 3

  OTTHUMT00000109349 ; CLCN5-005; intron 3

  OTTHUMT00000056542 ; CLCN5-001; intron 3

  OTTHUMT00000056543 ; CLCN5-002; intron 3

  OTTHUMT00000109349 ; CLCN5-005; intron 3

  ENST00000376088 ; CLCN5-001; intron 3

  ENST00000376091 ; CLCN5-002; intron 3

  ENST00000482218 ; CLCN5-005; intron 3

  ENST00000450422 ; CLCN5-201; intron 3

  ENST00000376088 ; CLCN5-001; intron 3

  ENST00000376091 ; CLCN5-002; intron 3

  ENST00000482218 ; CLCN5-005; intron 3

  ENST00000450422 ; CLCN5-201; intron 3

  ENST00000376088 ; CLCN5-001; intron 3

  ENST00000376091 ; CLCN5-002; intron 3

  ENST00000482218 ; CLCN5-005; intron 3

Clustered miRNAs

< 10kb from hsa-mir-500a

• hsa-mir-532: chrX: 49767754-49767844 [+]
• hsa-mir-188: chrX: 49768109-49768194 [+]
• hsa-mir-500a: chrX: 49773039-49773122 [+]
• hsa-mir-362: chrX: 49773572-49773636 [+]
• hsa-mir-501: chrX: 49774330-49774413 [+]
• hsa-mir-500b: chrX: 49775280-49775358 [+]
• hsa-mir-660: chrX: 49777849-49777945 [+]
• hsa-mir-502: chrX: 49779206-49779291 [+]

Database links

• EMBL: AY882306;AY882306
• ENTREZGENE: 574502;MIR500A
• HGNC: 32134;MIR500

Mature sequence hsa-miR-500a-5p

• Accession: MIMAT0004773
• Previous IDs: hsa-miR-500;hsa-miR-500a
• Sequence: 13 - uaauccuugcuaccugggugaga - 35
• Deep sequencing: 168 reads, 22 experiments
• Evidence: experimental; cloned [2]
• Predicted targets:
  • DIANA-MICROT:hsa-miR-500a-5p
  • MICRORNA.ORG:hsa-miR-500a-5p
  • MIRDB:hsa-miR-500a-5p
  • RNA22-HSA:hsa-miR-500a-5p
  • TARGETMINER:hsa-miR-500a-5p
  • TARGETSCAN-VERT:hsa-miR-500

Mature sequence hsa-miR-500a-3p

• Accession: MIMAT0002871
• Previous IDs: hsa-miR-500;hsa-miR-500*;hsa-miR-500a*
• Sequence: 52 - augcaccugggcaaggauucug - 73
• Deep sequencing: 4604 reads, 23 experiments
• Evidence: experimental; array-cloned [1], cloned [2]
• Predicted targets:
  • DIANA-MICROT:hsa-miR-500a-3p
  • MICRORNA.ORG:hsa-miR-500a-3p
  • MIRDB:hsa-miR-500a-3p
  • RNA22-HSA:hsa-miR-500a-3p
  • TARGETMINER:hsa-miR-500a-3p

References

1. PMID:15965474 "Identification of hundreds of conserved and nonconserved human microRNAs" Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z Nat Genet. 37:766-770(2005).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).