Stem-loop sequence hsa-mir-516a-1

Accession

MI0003180

Previous IDs

hsa-mir-516-1

Symbol

HGNC:MIR516A1

Description

Homo sapiens miR-516a-1 stem-loop

Gene family

MIPF0000020; mir-515

Stem-loop

                   c    aaa            guug  u 
ucucaggcugugaccuucu gagg   gaagcacuuucu    uc g
||||||||||||||||||| ||||   ||||||||||||    || a
agaguuuggcauugggaga uuuc   cuucgugaaaga    ag a
                   c    ---            --aa  a 

Deep sequencing

12 reads, 6 experiments

Genome context

• Coordinates (GRCh37.p5): chr19: 54259995-54260084 [+]
• Overlapping transcripts:

  intergenic

Clustered miRNAs

< 10kb from hsa-mir-516a-1

• hsa-mir-521-1: chr19: 54251890-54251976 [+]
• hsa-mir-522: chr19: 54254465-54254551 [+]
• hsa-mir-519a-1: chr19: 54255651-54255735 [+]
• hsa-mir-527: chr19: 54257272-54257356 [+]
• hsa-mir-516a-1: chr19: 54259995-54260084 [+]
• hsa-mir-1283-2: chr19: 54261486-54261572 [+]
• hsa-mir-516a-2: chr19: 54264387-54264476 [+]
• hsa-mir-519a-2: chr19: 54265598-54265684 [+]

Database links

• ENTREZGENE: 574498;MIR516A1
• HGNC: 32130;MIR516A1

Mature sequence hsa-miR-516a-5p

• Accession: MIMAT0004770
• Sequence: 16 - uucucgaggaaagaagcacuuuc - 38
• Deep sequencing: 20 reads, 5 experiments
• Evidence: experimental; cloned [2]
• Validated targets:
  • MIRECORDS:hsa-miR-516a-5p
  • TARBASE:hsa-miR-516a-5p
• Predicted targets:
  • DIANA-MICROT:hsa-miR-516a-5p
  • MICRORNA.ORG:hsa-miR-516a-5p
  • MIRDB:hsa-miR-516a-5p
  • RNA22-HSA:hsa-miR-516a-5p
  • TARGETMINER:hsa-miR-516a-5p
  • TARGETSCAN-VERT:hsa-miR-516a-5p

Mature sequence hsa-miR-516a-3p

• Accession: MIMAT0006778
• Sequence: 61 - ugcuuccuuucagagggu - 78
• Deep sequencing: 4 reads, 1 experiments
• Evidence: experimental; array-cloned [1]
• Validated targets:
  • MIRTARBASE:hsa-miR-516a-3p
• Predicted targets:
  • DIANA-MICROT:hsa-miR-516a-3p
  • MICRORNA.ORG:hsa-miR-516a-3p
  • MIRDB:hsa-miR-516a-3p
  • RNA22-HSA:hsa-miR-516a-3p
  • TARGETMINER:hsa-miR-516a-3p
  • TARGETSCAN-VERT:hsa-miR-516a-3p

References

1. PMID:15965474 "Identification of hundreds of conserved and nonconserved human microRNAs" Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z Nat Genet. 37:766-770(2005).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).