Stem-loop sequence hsa-mir-519a-1

Accession

MI0003178

Symbol

HGNC:MIR519A1

Description

Homo sapiens miR-519a-1 stem-loop

Gene family

MIPF0000020; mir-515

Stem-loop

       u                 a         guug  u 
cucaggc gugacacucuagaggga gcgcuuucu    uc g
||||||| ||||||||||||||||| |||||||||    || a
gaguuug cauugugagauuuuccu cgugaaagg    ag a
       u                 a         --aa  a 

Deep sequencing

37 reads, 8 experiments

Genome context

• Coordinates (GRCh37.p5): chr19: 54255651-54255735 [+]
• Overlapping transcripts:

  intergenic

Clustered miRNAs

< 10kb from hsa-mir-519a-1

• hsa-mir-520h: chr19: 54245766-54245853 [+]
• hsa-mir-521-1: chr19: 54251890-54251976 [+]
• hsa-mir-522: chr19: 54254465-54254551 [+]
• hsa-mir-519a-1: chr19: 54255651-54255735 [+]
• hsa-mir-527: chr19: 54257272-54257356 [+]
• hsa-mir-516a-1: chr19: 54259995-54260084 [+]
• hsa-mir-1283-2: chr19: 54261486-54261572 [+]
• hsa-mir-516a-2: chr19: 54264387-54264476 [+]
• hsa-mir-519a-2: chr19: 54265598-54265684 [+]

Database links

• EMBL: AY882326;AY882326
• ENTREZGENE: 574496;MIR519A1
• HGNC: 32128;MIR519A1

Mature sequence hsa-miR-519a-5p

• Accession: MIMAT0005452
• Previous IDs: hsa-miR-519a*
• Sequence: 15 - cucuagagggaagcgcuuucug - 36
• Deep sequencing: 8 reads, 4 experiments
• Evidence: experimental; array-cloned [1], cloned [2]
• Predicted targets:
  • DIANA-MICROT:hsa-miR-519a-5p
  • MICRORNA.ORG:hsa-miR-519a-5p
  • MIRDB:hsa-miR-519a-5p
  • RNA22-HSA:hsa-miR-519a-5p
  • TARGETMINER:hsa-miR-519a-5p

Mature sequence hsa-miR-519a-3p

• Accession: MIMAT0002869
• Previous IDs: hsa-miR-519a
• Sequence: 53 - aaagugcauccuuuuagagugu - 74
• Deep sequencing: 58 reads, 6 experiments
• Evidence: experimental; array-cloned [1], cloned [2]
• Validated targets:
  • TARBASE:hsa-miR-519a-3p
• Predicted targets:
  • DIANA-MICROT:hsa-miR-519a-3p
  • MICRORNA.ORG:hsa-miR-519a-3p
  • MIRDB:hsa-miR-519a-3p
  • RNA22-HSA:hsa-miR-519a-3p
  • TARGETMINER:hsa-miR-519a-3p
  • TARGETSCAN-VERT:hsa-miR-519a

References

1. PMID:15965474 "Identification of hundreds of conserved and nonconserved human microRNAs" Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z Nat Genet. 37:766-770(2005).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).