Stem-loop sequence hsa-mir-522

Accession

MI0003177

Symbol

HGNC:MIR522

Description

Homo sapiens miR-522 stem-loop

Gene family

MIPF0000020; mir-515

Stem-loop

      -  u   u c            g  c     guug  u 
ucucag gc gug c cucuagagggaa cg uuucu    uc g
|||||| || ||| | |||||||||||| || |||||    || a
agaguu cg cau g gagauuucccuu gu aaaga    ag a
      u  -   u u            g  a     --aa  a 

Deep sequencing

12 reads, 4 experiments

Genome context

• Coordinates (GRCh37.p5): chr19: 54254465-54254551 [+]
• Overlapping transcripts:

  intergenic

Clustered miRNAs

< 10kb from hsa-mir-522

• hsa-mir-517c: chr19: 54244567-54244661 [+]
• hsa-mir-520h: chr19: 54245766-54245853 [+]
• hsa-mir-521-1: chr19: 54251890-54251976 [+]
• hsa-mir-522: chr19: 54254465-54254551 [+]
• hsa-mir-519a-1: chr19: 54255651-54255735 [+]
• hsa-mir-527: chr19: 54257272-54257356 [+]
• hsa-mir-516a-1: chr19: 54259995-54260084 [+]
• hsa-mir-1283-2: chr19: 54261486-54261572 [+]
• hsa-mir-516a-2: chr19: 54264387-54264476 [+]

Database links

• EMBL: AY785936;AY785936
• EMBL: AY882326;AY882326
• ENTREZGENE: 574495;MIR522
• HGNC: 32127;MIR522

Mature sequence hsa-miR-522-5p

• Accession: MIMAT0005451
• Previous IDs: hsa-miR-522*
• Sequence: 16 - cucuagagggaagcgcuuucug - 37
• Deep sequencing: 8 reads, 2 experiments
• Evidence: experimental; array-cloned [1], cloned [2]
• Predicted targets:
  • DIANA-MICROT:hsa-miR-522-5p
  • MICRORNA.ORG:hsa-miR-522-5p
  • MIRDB:hsa-miR-522-5p
  • RNA22-HSA:hsa-miR-522-5p
  • TARGETMINER:hsa-miR-522-5p

Mature sequence hsa-miR-522-3p

• Accession: MIMAT0002868
• Previous IDs: hsa-miR-522
• Sequence: 54 - aaaaugguucccuuuagagugu - 75
• Deep sequencing: 2 reads, 1 experiments
• Evidence: experimental; array-cloned [1], cloned [2-3]
• Predicted targets:
  • DIANA-MICROT:hsa-miR-522-3p
  • MICRORNA.ORG:hsa-miR-522-3p
  • MIRDB:hsa-miR-522-3p
  • RNA22-HSA:hsa-miR-522-3p
  • TARGETMINER:hsa-miR-522-3p
  • TARGETSCAN-VERT:hsa-miR-522

References

1. PMID:15965474 "Identification of hundreds of conserved and nonconserved human microRNAs" Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z Nat Genet. 37:766-770(2005).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
3. PMID:17616659 "Patterns of known and novel small RNAs in human cervical cancer" Lui WO, Pourmand N, Patterson BK, Fire A Cancer Res. 67:6031-6043(2007).