Stem-loop sequence hsa-mir-518d

Accession

MI0003171

Symbol

HGNC:MIR518D

Description

Homo sapiens miR-518d stem-loop

Gene family

MIPF0000020; mir-515

Stem-loop

  c  u        c              a    cu   g  u 
uc ca gcugugac cucuagagggaagc cuuu  guu uc g
|| || |||||||| |||||||||||||| ||||  ||| || a
ag gu uggcauug gagguuucccuucg gaaa  caa ag a
  a  u        c              c    -c   -  a 

Deep sequencing

13 reads, 4 experiments

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context

• Coordinates (GRCh37.p5): chr19: 54238131-54238217 [+]
• Overlapping transcripts:

  intergenic

Clustered miRNAs

< 10kb from hsa-mir-518d

• hsa-mir-516b-2: chr19: 54228696-54228780 [+]
• hsa-mir-526a-2: chr19: 54230176-54230240 [+]
• hsa-mir-518e: chr19: 54233092-54233179 [+]
• hsa-mir-518a-1: chr19: 54234260-54234344 [+]
• hsa-mir-518d: chr19: 54238131-54238217 [+]
• hsa-mir-516b-1: chr19: 54240099-54240188 [+]
• hsa-mir-518a-2: chr19: 54242587-54242673 [+]
• hsa-mir-517c: chr19: 54244567-54244661 [+]
• hsa-mir-520h: chr19: 54245766-54245853 [+]

Database links

• EMBL: AY785916;AY785916
• EMBL: AY882327;AY882327
• EMBL: AY882336;AY882336
• ENTREZGENE: 574489;MIR518D
• HGNC: 32121;MIR518D

Mature sequence hsa-miR-518d-5p

• Accession: MIMAT0005456
• Sequence: 16 - cucuagagggaagcacuuucug - 37
• Deep sequencing: 11 reads, 2 experiments
• Evidence: experimental; array-cloned [1], cloned [2]
• Predicted targets:
  • DIANA-MICROT:hsa-miR-518d-5p
  • MICRORNA.ORG:hsa-miR-518d-5p
  • MIRDB:hsa-miR-518d-5p
  • RNA22-HSA:hsa-miR-518d-5p
  • TARGETMINER:hsa-miR-518d-5p
  • TARGETSCAN-VERT:hsa-miR-518d-5p

Mature sequence hsa-miR-518d-3p

• Accession: MIMAT0002864
• Previous IDs: hsa-miR-518d
• Sequence: 53 - caaagcgcuucccuuuggagc - 73
• Deep sequencing: 2 reads, 2 experiments
• Evidence: experimental; array-cloned [1]
• Predicted targets:
  • DIANA-MICROT:hsa-miR-518d-3p
  • MICRORNA.ORG:hsa-miR-518d-3p
  • MIRDB:hsa-miR-518d-3p
  • RNA22-HSA:hsa-miR-518d-3p
  • TARGETMINER:hsa-miR-518d-3p
  • TARGETSCAN-VERT:hsa-miR-518d-3p

References

1. PMID:15965474 "Identification of hundreds of conserved and nonconserved human microRNAs" Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z Nat Genet. 37:766-770(2005).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).